UP_Q8JHE1

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SequenceILGPVLGLVSDTLDDVLGIL
FunctionsMaximin-3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria. It shows also antimicrobial activity against the fungus C.albicans, but not against A.flavus nor P.uticale. It has little hemolytic activity. It possess a significant cytotoxicity against tumor cell lines. It possess a significant anti-HIV activity. It shows high spermicidal activity. Maximin-H5 shows antibacterial activity only against the Gram-positive bacteria S.aureus. The other bacterial and fungal strains tested were resistant to it. The presence of metal ions, like Zn(2+) and Mg(2+), did not increase its antimicrobial potency. Does not show hemolytic activity (in a concentration up to 80 uM).
Source#Synthetic
Solubility-20°C
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