We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy
Ac-ANW-AMC is a fluorogenic peptide substrate and used for measuring chymotrypsin-like activity of the immunoproteasome.This substrate is specific to the immunoproteasome, and is not hydrolyzed efficiently by the constitutive proteasome. Cleavage of this peptide by the immunoproteasome or other enzymes liberates the fluorophore AMC causing a strong fluorescent signal which is detected at an Excitation wavelength of 345nm and Emission wavelength of 445nm.
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.F/Formula | C30H32N6O7 |
M.W/Mr. | 588.6 |
Sequence | Acetyl-Ala-Asn-Trp-7-amido-4-methylcoumarin |
Application | Ac-ANW-AMC (Acetyl-Ala-Asn-Trp-AMC) is a 7-amino-4-methylcoumarin labeled fluorogenic peptidyl substrate hydrolyzed by the β5i subunit of the 20S immunoproteasome. |
Appearance | Lyophilized powder |
Purity | >99% |
Source# | Synthetic |
Long-term Storage Conditions | Soluble in DMSO |
InChI Key | ORTKHFLJSJQDKO-ZCWWJEROSA-N |
1. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at info@creative-peptides.com. We will endeavor to provide highly satisfying products and services.