Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide

Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide contains stereochemical substitutions and cysteine residues capable of forming stabilizing motifs. The acetylated and amidated termini support enhanced structural definition. Its modified framework is used to probe melanocortin recognition and folding behavior. Researchers employ it in peptide design and conformational analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide(CAS 819048-44-7)

CAT No: M2729

CAS No:819048-44-7

Synonyms/Alias:819048-44-7;AC-D-ARG-CYS-GLU-HIS-D-PHE-ARG-TRP-CYS-NH2;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C51H72N18O11S2
M.W/Mr.
1177.4
Sequence
One Letter Code:RCEHFRWC
Three Letter Code:Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH2
InChI
InChI=1S/C51H72N18O11S2/c1-27(70)62-33(13-7-17-58-50(53)54)43(74)69-40(25-82)49(80)64-35(15-16-41(71)72)45(76)67-38(21-30-23-57-26-61-30)48(79)65-36(19-28-9-3-2-4-10-28)46(77)63-34(14-8-18-59-51(55)56)44(75)66-37(47(78)68-39(24-81)42(52)73)20-29-22-60-32-12-6-5-11-31(29)32/h2-6,9-12,22-23,26,33-40,60,81-82H,7-8,13-21,24-25H2,1H3,(H2,52,73)(H,57,61)(H,62,70)(H,63,77)(H,64,80)(H,65,79)(H,66,75)(H,67,76)(H,68,78)(H,69,74)(H,71,72)(H4,53,54,58)(H4,55,56,59)/t33-,34+,35+,36-,37+,38+,39+,40+/m1/s1
InChI Key
ZUGUOZWTPYJYJW-ZSTGMXRXSA-N

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