APC 366
An elective, selective inhibitor of the mast cell tryptase, which inhibits tryptase-induced histamine release from human tonsil and lung cells. It can reduce airway inflammation and block postchallenge airway hyperresponsiveness in vivo.
Online Inquiry
| CAT# | R0892 |
| CAS | 158921-85-8 |
| Synonyms/Alias | N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide |
| M.F/Formula | C22H28N6O4 |
| M.W/Mr. | 440.5 |
| Sequence | N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide |
| Labeling Target | Tryptase |
| Appearance | White lyophilised solid |
| Purity | >98% |
| Activity | Inhibitor |
| Source# | Synthetic |
Storage | -20°C |
Long-term Storage Conditions | -20 °C |
InChI | InChI=1S/C22H28N6O4/c23-19(30)17-8-4-12-28(17)21(32)16(7-3-11-26-22(24)25)27-20(31)15-10-9-13-5-1-2-6-14(13)18(15)29/h1-2,5-6,9-10,16-17,29H,3-4,7-8,11-12H2,(H2,23,30)(H,27,31)(H4,24,25,26)/t16-,17-/m0/s1 |
InChI Key | SKYWIMYOGAWOMB-IRXDYDNUSA-N |
Isomeric SMILES | C1C[C@H](N(C1)C(=O)[C@H](CCCN=C(N)N)NC(=O)C2=C(C3=CC=CC=C3C=C2)O)C(=O)N |
Write a review
Ask a question
My Review for APC 366
Required fields are marked with *
×
Ask a Question for APC 366
Required fields are marked with *
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
