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aStAx-35R

aStAx-35R is a stapled α-helical peptide containing a sequence designed for strong structural rigidity and enhanced binding affinity. The hydrocarbon staple enforces helical geometry and improves proteolytic stability. Researchers leverage its constrained architecture to study protein-protein interaction interfaces. Applications include stapled-peptide design, conformational control, and ligand optimization.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
aStAx-35R(CAS 1418863-17-8)

CAT No: R2608

CAS No:1418863-17-8

Synonyms/Alias:aStAx-35R;EX-A9239;HY-P10392;CS-1054504;1418863-17-8;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C111H178N40O20
M.W/Mr.
2392.9
InChI
InChI=1S/C111H178N40O20/c1-12-62(8)86-100(168)142-77(50-59(2)3)92(160)141-80(54-83(153)154)96(164)150-110(10,41-21-15-13-14-16-22-42-111(11,103(171)148-86)149-95(163)76(39-28-48-131-109(123)124)139-97(165)82-40-29-49-151(82)101(169)81(52-65-56-133-70-33-20-18-31-68(65)70)144-90(158)73(36-25-45-128-106(117)118)137-88(156)72(135-63(9)152)35-24-44-127-105(115)116)102(170)145-79(53-66-57-125-58-134-66)94(162)147-84(60(4)5)98(166)140-74(37-26-46-129-107(119)120)89(157)138-75(38-27-47-130-108(121)122)91(159)146-85(61(6)7)99(167)143-78(51-64-55-132-69-32-19-17-30-67(64)69)93(161)136-71(87(112)155)34-23-43-126-104(113)114/h13-14,17-20,30-33,55-62,71-82,84-86,132-133H,12,15-16,21-29,34-54H2,1-11H3,(H2,112,155)(H,125,134)(H,135,152)(H,136,161)(H,137,156)(H,138,157)(H,139,165)(H,140,166)(H,141,160)(H,142,168)(H,143,167)(H,144,158)(H,145,170)(H,146,159)(H,147,162)(H,148,171)(H,149,163)(H,150,164)(H,153,154)(H4,113,114,126)(H4,115,116,127)(H4,117,118,128)(H4,119,120,129)(H4,121,122,130)(H4,123,124,131)/b14-13+/t62-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,84-,85-,86-,110-,111-/m0/s1
InChI Key
BTMNVNJATGXPJV-RQJMDJBWSA-N

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