aStAx-35R is a stapled α-helical peptide containing a sequence designed for strong structural rigidity and enhanced binding affinity. The hydrocarbon staple enforces helical geometry and improves proteolytic stability. Researchers leverage its constrained architecture to study protein-protein interaction interfaces. Applications include stapled-peptide design, conformational control, and ligand optimization.
CAT No: R2608
CAS No:1418863-17-8
Synonyms/Alias:aStAx-35R;EX-A9239;HY-P10392;CS-1054504;1418863-17-8;
aStAx-35R is a specialized carbohydrate compound designed for advanced research and development across multiple scientific disciplines. Characterized by its unique structural configuration, aStAx-35R offers exceptional versatility in biochemical and analytical applications. Its robust molecular architecture enables reliable interaction with a variety of biological molecules, making it an invaluable resource for researchers seeking to explore carbohydrate-mediated processes. The compound's high solubility and stability under diverse laboratory conditions further enhance its suitability for both in vitro and in vivo experimentation. Researchers benefit from its consistent performance, which supports reproducible results in complex experimental setups. The availability of aStAx-35R has expanded the possibilities for innovation in fields that rely on precise carbohydrate manipulation and analysis.
Glycobiology Research: aStAx-35R plays a pivotal role in the study of glycan structures and their biological functions. By serving as a model carbohydrate, it enables scientists to dissect the intricate interactions between sugars and proteins, such as lectins or enzymes. Its defined structure allows for controlled experimentation, facilitating the elucidation of mechanisms underlying cell signaling, molecular recognition, and immune response modulation. Researchers utilize the compound to map glycosylation patterns and investigate the role of specific carbohydrate motifs in health and disease models. The compound's compatibility with a variety of detection and labeling techniques further enhances its utility in detailed glycomic profiling.
Enzyme Substrate Analysis: As a substrate in enzymatic assays, aStAx-35R provides a reliable platform for evaluating the activity and specificity of carbohydrate-processing enzymes. Its structural attributes make it particularly suitable for studying glycosidases, glycosyltransferases, and other carbohydrate-modifying proteins. By incorporating aStAx-35R into in vitro assays, researchers can monitor enzymatic reactions in real time, identify catalytic mechanisms, and screen for potential enzyme inhibitors or activators. The compound's performance in kinetic studies aids in the characterization of enzyme-substrate interactions, supporting the development of novel biocatalysts and therapeutic candidates.
Analytical Chemistry and Detection Methods: In the realm of analytical chemistry, aStAx-35R is employed as a standard or reference material for the calibration and validation of carbohydrate detection techniques. Its well-defined properties make it ideal for use in chromatographic, spectrometric, and electrophoretic analyses. Scientists utilize the compound to optimize detection sensitivity, assess method reproducibility, and establish quantification protocols for complex carbohydrate mixtures. The availability of aStAx-35R contributes to the advancement of high-throughput analytical platforms, enabling more accurate and efficient profiling of glycans in various biological samples.
Material Science and Biomaterials: The unique physicochemical characteristics of aStAx-35R have spurred its adoption in the development of novel biomaterials. Researchers integrate the compound into hydrogels, films, and scaffolds to modulate surface properties and enhance biocompatibility. Its ability to mediate cell adhesion and proliferation is leveraged in tissue engineering and regenerative medicine research, where controlled carbohydrate presentation is critical for guiding cellular behavior. The compound's stability and tunable functional groups allow for the customization of material properties, supporting the design of advanced biomimetic systems for a range of experimental applications.
Drug Discovery and Screening: aStAx-35R is increasingly utilized in drug discovery pipelines, particularly for high-throughput screening of carbohydrate-binding proteins and small molecules. Its defined structure enables the systematic evaluation of ligand-receptor interactions, facilitating the identification of potential therapeutic leads. Researchers employ the compound in binding assays, microarrays, and biosensor platforms to investigate the specificity and affinity of candidate molecules. By supporting the rational design of carbohydrate-targeted agents, aStAx-35R accelerates the development of innovative strategies for modulating biological pathways relevant to disease intervention and prevention.
1. TMEM16F and dynamins control expansive plasma membrane reservoirs
2. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More