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Endothelin-3, human, mouse, rabbit, rat

Endothelin-3, human, mouse, rabbit, rat is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Endothelin-3, human, mouse, rabbit, rat(CAS 117399-93-6)

CAT No: R1342

CAS No:117399-93-6

Synonyms/Alias:Endothelin III;117399-93-6;Rat endothelin-3;Human endothelin-3;Endothelin-3 (human);UNII-0066WLJ02E;Endothelin 3 (mouse intestine);0066WLJ02E;Endothelin-3, human, mouse, rabbit, rat;Cys-thr-cys-phe-thr-tyr-lys-asp-lys-glu-cys-val-tyr-tyr-cys-his-leu-asp-ile-ile-trp (1-15 disulfide, 3-11 disulfide);Endothelin 1 (pig), 2-L-threonine-4-L-phenylalanine-5-L-threonine-6-L-tyrosine-7-L-lysine-14-L-tyrosine-;AKOS024456427;DA-52898;PD076229;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C121H168N26O33S4
M.W/Mr.
2643.1
Sequence
One Letter Code:CTCFTYKDKECVYYCHLDIIW
Three Letter Code:H-Cys(1)-Thr-Cys(2)-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys(2)-Val-Tyr-Tyr-Cys(1)-His-Leu-Asp-Ile-Ile-Trp-OH
Application
Cardiovascular System & Diseases
Appearance
Supplied as a trifluoroacetate salt. Sold on the basis of peptide content.
Purity
≥97% (HPLC)
Long-term Storage Conditions
5% acetic acid: 0.5 mg/mL
InChI
InChI=1S/C121H168N26O33S4/c1-11-62(7)97(117(175)139-89(121(179)180)49-70-53-126-77-25-17-16-24-75(70)77)145-118(176)98(63(8)12-2)144-112(170)88(52-95(157)158)136-105(163)81(44-60(3)4)131-109(167)86(50-71-54-125-59-127-71)134-113(171)90-56-182-181-55-76(124)101(159)146-99(64(9)148)120(178)142-91-57-183-184-58-92(115(173)143-96(61(5)6)116(174)137-84(48-69-32-38-74(152)39-33-69)107(165)132-82(108(166)141-90)46-67-28-34-72(150)35-29-67)140-104(162)80(40-41-93(153)154)130-102(160)78(26-18-20-42-122)129-110(168)87(51-94(155)156)135-103(161)79(27-19-21-43-123)128-106(164)83(47-68-30-36-73(151)37-31-68)138-119(177)100(65(10)149)147-111(169)85(133-114(91)172)45-66-22-14-13-15-23-66/h13-17,22-25,28-39,53-54,59-65,76,78-92,96-100,126,148-152H,11-12,18-21,26-27,40-52,55-58,122-124H2,1-10H3,(H,125,127)(H,128,164)(H,129,168)(H,130,160)(H,131,167)(H,132,165)(H,133,172)(H,134,171)(H,135,161)(H,136,163)(H,137,174)(H,138,177)(H,139,175)(H,140,162)(H,141,166)(H,142,178)(H,143,173)(H,144,170)(H,145,176)(H,146,159)(H,147,169)(H,153,154)(H,155,156)(H,157,158)(H,179,180)/t62-,63-,64+,65+,76-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,96-,97-,98-,99-,100-/m0/s1
InChI Key
OQGZWNZGVYLIFX-JQWUVQPESA-N

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