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LTX-315

LTX-315 is an oncolytic peptide with potent anticancer activity; inhibits MRC-5, A20 and AT84 with IC50s of 34.3, 8.3 and 11 μM, respectively.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
LTX-315(CAS 1345407-05-7)

CAT No: R1491

CAS No:1345407-05-7

Synonyms/Alias:LTX-315;1345407-05-7;Oncopore;Ruxotemitide;Kkwwkkwdipk-nh2;ruxotemitida;Kkwwkkw-.beta.-phenyl-fk-nh2;LTX 315;RUXOTEMITIDE [INN];UNII-75FBL12IZ7;75FBL12IZ7;(S)-2,6-diamino-N-((5S,8S,11S,14S,17S,20S,23S,26S)-11,20,23-tris((1H-indol-3-yl)methyl)-1,30-diamino-14,17-bis(4-aminobutyl)-8-benzhydryl-5-carbamoyl-7,10,13,16,19,22,25-heptaoxo-6,9,12,15,18,21,24-heptaazatriacontan-26-yl)hexanamide;L-LYSINAMIDE, L-LYSYL-L-LYSYL-L-TRYPTOPHYL-L-TRYPTOPHYL-L-LYSYL-L-LYSYL-L-TRYPTOPHYL-.BETA.-PHENYL-L-PHENYLALANYL-;ruxotemitidum;CHEMBL4297628;LTX 315 [WHO-DD];KKWWKKW-BETA-PHENYL-FK-NH2;s8199;AKOS032945178;CCG-270681;CS-6979;DB12748;BS-15278;DA-65090;HY-19894;D84062;Q27266383;(2S)-6-AMINO-2-[(2S)-2-[(2S)-2-[(2S)-6-AMINO-2-[(2S)-6-AMINO-2-[(2S)-2-[(2S)-2-[(2S)-6-AMINO-2-[(2S)-2,6-DIAMINOHEXANAMIDO]HEXANAMIDO]-3-(1H-INDOL-3-YL)PROPANAMIDO]-3-(1H-INDOL-3-YL)PROPANAMIDO]HEXANAMIDO]HEXANAMIDO]-3-(1H-INDOL-3-YL)PROPANAMIDO]-3,3-DIPHENYLPROPANAMIDO]HEXANAMIDE;L-LYSINAMIDE, L-LYSYL-L-LYSYL-L-TRYPTOPHYL-L-TRYPTOPHYL-L-LYSYL-L-LYSYL-L-TRYPTOPHYL-BETA-PHENYL-L-PHENYLALANYL-;

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M.F/Formula
C78H106N18O9
M.W/Mr.
1439.8
Sequence
One Letter Code:KKWWKKWXK
Three Letter Code:H-Lys-Lys-Trp-Trp-Lys-Lys-Trp-Dip-Lys-NH2
InChI
InChI=1S/C78H106N18O9/c79-38-18-13-30-57(84)71(98)90-62(35-15-20-40-81)73(100)93-66(44-52-47-87-59-32-11-8-28-55(52)59)76(103)95-65(43-51-46-86-58-31-10-7-27-54(51)58)75(102)92-63(36-16-21-41-82)72(99)91-64(37-17-22-42-83)74(101)94-67(45-53-48-88-60-33-12-9-29-56(53)60)77(104)96-69(78(105)89-61(70(85)97)34-14-19-39-80)68(49-23-3-1-4-24-49)50-25-5-2-6-26-50/h1-12,23-29,31-33,46-48,57,61-69,86-88H,13-22,30,34-45,79-84H2,(H2,85,97)(H,89,105)(H,90,98)(H,91,99)(H,92,102)(H,93,100)(H,94,101)(H,95,103)(H,96,104)/t57-,61-,62-,63-,64-,65-,66-,67-,69-/m0/s1
InChI Key
GGAKLYWEFZCVIT-TVEKFXMRSA-N

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