Nociceptin, a heptadecapeptide, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic.
CAT No: R1564
CAS No: 170713-75-4
Synonyms/Alias: Nociceptin;Orphanin FQ;170713-75-4;Orphanin FQ (swine);Orphanin FQ (rat);Orphanin FQ (human);Nociceptin/orphanin FQ;Human nociceptin;Nociceptin (1-17);N-OFQ peptide;Nociceptin (human);Orphanin FQ (pig);nociceptin-orphanin FQ;FGGFTGARKSARKLANQ;7AYI9N34FF;CHEBI:80266;NOCICEPTIN [MI];DTXSID60168933;L-Glutamine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparaginyl-;PheGlyGlyPheThrGlyAlaArgLysSerAlaArgLysLeuAlaAsnGln;Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln;PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-UNK-ALA-ARG-LYS-LEU-ALA-ASN-GLN;L-Phe-Gly-Gly-L-Phe-L-Thr-Gly-L-Ala-L-Arg-L-Lys-L-Ser-L-Ala-L-Arg-L-Lys-L-Leu-L-Ala-L-Asn-L-Gln;L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparaginyl-L-glutamine;UNII-7AYI9N34FF;orphanin-fq;Nociceptin(Orphanin FQ);CHEMBL396460;GTPL1681;DTXCID1091424;BDBM50004178;HB2424;AKOS024458690;C79H129N27O22;NCGC00167266-01;DA-76240;FN108853;TS-10285;Q4327722;BRD-K05717154-001-01-1;
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M.F/Formula | C79H129N27O22 |
M.W/Mr. | 1809 |
Sequence | One Letter Code:FGGFTGARKSARKLANQ Three Letter Code:H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH |
Purity | ≥98% (HPLC) |
Source# | Synthetic |
Long-term Storage Conditions | Soluble to 1 mg/ml in water |
Shipping Condition | Ambient temperature only |
InChI | InChI=1S/C79H129N27O22/c1-41(2)33-54(72(122)95-44(5)66(116)103-56(36-59(84)110)73(123)102-53(77(127)128)27-28-58(83)109)104-70(120)49(23-13-15-29-80)100-69(119)52(26-18-32-90-79(87)88)99-65(115)43(4)96-75(125)57(40-107)105-71(121)50(24-14-16-30-81)101-68(118)51(25-17-31-89-78(85)86)98-64(114)42(3)94-61(112)39-93-76(126)63(45(6)108)106-74(124)55(35-47-21-11-8-12-22-47)97-62(113)38-91-60(111)37-92-67(117)48(82)34-46-19-9-7-10-20-46/h7-12,19-22,41-45,48-57,63,107-108H,13-18,23-40,80-82H2,1-6H3,(H2,83,109)(H2,84,110)(H,91,111)(H,92,117)(H,93,126)(H,94,112)(H,95,122)(H,96,125)(H,97,113)(H,98,114)(H,99,115)(H,100,119)(H,101,118)(H,102,123)(H,103,116)(H,104,120)(H,105,121)(H,106,124)(H,127,128)(H4,85,86,89)(H4,87,88,90)/t42-,43-,44-,45+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-/m0/s1 |
InChI Key | PULGYDLMFSFVBL-SMFNREODSA-N |
Canonical SMILES | O=C([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O)N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC(N)=O)=O)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)C)=O)CO |
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