Pyr-Arg-Thr-Lys-Arg-AMC TFA combines a pyroglutamate cap, basic residues, and a fluorogenic AMC group for sensitive cleavage detection. Charged side chains assist solubility and enzyme recognition. Researchers analyze its kinetics to characterize protease activity. Use spans fluorescence-based assays, substrate evaluation, and mechanistic profiling.
CAT No: R2436
CAS No:1255501-99-5
Synonyms/Alias:1255501-99-5;Pyr-Arg-Thr-Lys-Arg-AMC TFA;Pyr-Arg-Thr-Lys-Arg-AMC (TFA);Pyr-Arg-Thr-Lys-Arg-AMC trifluoroacetate;(2S)-N-[(2S)-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-5-oxopyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid;HY-P4349A;MFCD17215945;L-Pyroglutamyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin trifluoroacetate salt;Pyr-Arg-Thr-Lys-Arg-AMCtrifluoroacetate;DA-57259;CS-0693663;pGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin trifluoroacetate salt, >=96% (HPLC);
3. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
4. Emu oil in combination with other active ingredients for treating skin imperfections
5. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
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