Reversin 121 serves as a selective modulator of the renowned ABCG2 transporter, boasts remarkable potential to combat drug resistance phenomena. Through synergistic interactions with renowned chemotherapy agents like doxorubicin, this intervention showcases augmented efficacy, revolutionizing the treatment landscape. When employed within biomedicine research, Reversin 121 emerges as an indispensable ally, effectively surmounting multidrug resistance hurdles, and promising remarkable amelioration of treatment outcomes.
CAT No: R2073
CAS No: 174630-04-7
Synonyms/Alias: reversin 121;174630-04-7;CHEMBL221390;tert-butyl (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoate;Boc-Asp(Obzl)-Lys(Z)-OtBu;tert-butyl (2S)-2-((2S)-4-(benzyloxy)-2-(((tert-butoxy)carbonyl)amino)-4-oxobutanamido)-6-(((benzyloxy)carbonyl)amino)hexanoate;tert-butyl (2S)-2-[(2S)-4-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}-4-oxobutanamido]-6-{[(benzyloxy)carbonyl]amino}hexanoate;R121 peptide;chemosensitizer 121;BDBM50326927;DB14072;DA-57408;HY-125486;Reversin 121, >=97% (HPLC), powder;CS-0091919;NS00072588;(S)-tert-butyl 2-((S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)-4-oxobutanamido)-6-(benzyloxycarbonylamino)hexanoate;2-(1,1-dimethylethyl) 1-(phenylmethyl) ester N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl-N6-[(phenylmethoxy)carbonyl]-L-lysine;tert-Butyl N2-((S)-4-(benzyloxy)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoyl)-N6-((benzyloxy)carbonyl)-L-lysinate;
Chemical Name: tert-butyl (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoate
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M.F/Formula | C34H47N3O9 |
M.W/Mr. | 641.8 |
Sequence | Three Letter Code:Boc-Asp(OBn)-Lys(Cbz)-OtBu |
InChI | InChI=1S/C34H47N3O9/c1-33(2,3)45-30(40)26(19-13-14-20-35-31(41)44-23-25-17-11-8-12-18-25)36-29(39)27(37-32(42)46-34(4,5)6)21-28(38)43-22-24-15-9-7-10-16-24/h7-12,15-18,26-27H,13-14,19-23H2,1-6H3,(H,35,41)(H,36,39)(H,37,42)/t26-,27-/m0/s1 |
InChI Key | SVNKEDMVAQBLLN-SVBPBHIXSA-N |
Canonical SMILES | CC(C)(C)OC(=O)C(CCCCNC(=O)OCC1=CC=CC=C1)NC(=O)C(CC(=O)OCC2=CC=CC=C2)NC(=O)OC(C)(C)C |
Isomeric SMILES | CC(C)(C)OC(=O)[C@H](CCCCNC(=O)OCC1=CC=CC=C1)NC(=O)[C@H](CC(=O)OCC2=CC=CC=C2)NC(=O)OC(C)(C)C |
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