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Reversin 121

Reversin 121 serves as a selective modulator of the renowned ABCG2 transporter, boasts remarkable potential to combat drug resistance phenomena. Through synergistic interactions with renowned chemotherapy agents like doxorubicin, this intervention showcases augmented efficacy, revolutionizing the treatment landscape. When employed within biomedicine research, Reversin 121 emerges as an indispensable ally, effectively surmounting multidrug resistance hurdles, and promising remarkable amelioration of treatment outcomes.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R2073

CAS No:174630-04-7

Synonyms/Alias:reversin 121;174630-04-7;CHEMBL221390;tert-butyl (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoate;Boc-Asp(Obzl)-Lys(Z)-OtBu;tert-butyl (2S)-2-((2S)-4-(benzyloxy)-2-(((tert-butoxy)carbonyl)amino)-4-oxobutanamido)-6-(((benzyloxy)carbonyl)amino)hexanoate;tert-butyl (2S)-2-[(2S)-4-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}-4-oxobutanamido]-6-{[(benzyloxy)carbonyl]amino}hexanoate;R121 peptide;chemosensitizer 121;BDBM50326927;DB14072;DA-57408;HY-125486;Reversin 121, >=97% (HPLC), powder;CS-0091919;NS00072588;(S)-tert-butyl 2-((S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)-4-oxobutanamido)-6-(benzyloxycarbonylamino)hexanoate;2-(1,1-dimethylethyl) 1-(phenylmethyl) ester N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl-N6-[(phenylmethoxy)carbonyl]-L-lysine;tert-Butyl N2-((S)-4-(benzyloxy)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoyl)-N6-((benzyloxy)carbonyl)-L-lysinate;

Chemical Name:tert-butyl (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoate

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M.F/Formula
C34H47N3O9
M.W/Mr.
641.8
Sequence
Three Letter Code:Boc-Asp(OBn)-Lys(Cbz)-OtBu
InChI
InChI=1S/C34H47N3O9/c1-33(2,3)45-30(40)26(19-13-14-20-35-31(41)44-23-25-17-11-8-12-18-25)36-29(39)27(37-32(42)46-34(4,5)6)21-28(38)43-22-24-15-9-7-10-16-24/h7-12,15-18,26-27H,13-14,19-23H2,1-6H3,(H,35,41)(H,36,39)(H,37,42)/t26-,27-/m0/s1
InChI Key
SVNKEDMVAQBLLN-SVBPBHIXSA-N
Canonical SMILES
CC(C)(C)OC(=O)C(CCCCNC(=O)OCC1=CC=CC=C1)NC(=O)C(CC(=O)OCC2=CC=CC=C2)NC(=O)OC(C)(C)C
Isomeric SMILES
CC(C)(C)OC(=O)[C@H](CCCCNC(=O)OCC1=CC=CC=C1)NC(=O)[C@H](CC(=O)OCC2=CC=CC=C2)NC(=O)OC(C)(C)C

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