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UP_P83663

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X20007

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
Sequence
SAPRGCWTKSYPPKPCK
Functions
Has antibacterial activity against Gram-positive bacteria B.megaterium Bm11, S.lentus and M.luteus, Gram-negative bacteria Y.pseudotuberculosis YP III and P.syringae pv tabaci, and antifungal activity against C.tropicalis, C.guiller-mondii and P.nicotianae spores. Has hemolytic activity. The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity. Probably binds to the outer membrane surface before aggregating to form transmembrane pores.
Source#
Synthetic
Solubility
-20°C

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