Z-L-aspartic acid β-cyclohexyl ester is an L-aspartic acid derivative in which the side-chain carboxyl group is esterified with a cyclohexyl moiety at the β-position, while the α-amino and α-carboxyl functionalities remain part of the aspartate scaffold. The molecule contains an amino acid backbone with an α-carboxyl group and an N-protecting Z (benzyloxycarbonyl, Cbz) group, and the β-carboxyl is converted from a free carboxylic acid into a cyclohexyl ester, reducing its acidity and changing hydrogen-bonding behavior relative to the unprotected amino acid. This protected ester form is used as a precursor in peptide and amino acid derivative synthesis and as a substrate-like building block for preparing aspartate-containing conjugates, where controlled chemoselectivity and temporary masking of the β-carboxyl group help direct subsequent coupling and functional-group transformations.
CAT No: CP00434
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