Z-L-Dap-OMe*HCl

Name: Z-L-Dap-OMe*HCl
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-L-Dap-OMe*HCl is a protected amino acid methyl ester hydrochloride derivative of L-2,3-diaminopropanoic acid (L-Dap), bearing a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality and a methyl ester (OMe) on the carboxyl group. The molecule contains two amino groups on the side chain, with the carboxyl functionality converted to an ester and the overall salt form indicated by "*HCl," while the "L" stereochemical designation is explicitly specified in the name. This amino acid derivative is used as a building block for peptide and peptidomimetic synthesis and for preparing amino acid analogues where controlled protection of the amino and carboxyl functionalities supports stepwise coupling and subsequent deprotection strategies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25795

CAS No:35761-27-4

Synonyms/Alias:METHYL2-(S)-[N-CARBOBENZYLOXY]AMINO-3-AMINOPROPIONATE,HYDROCHLORIDE;35761-27-4;C12H16N2O4.HCl;SCHEMBL3258256;OLOFLUKZNNTGBC-PPHPATTJSA-N;7373AH;AKOS025402659;AK175772;BP-11095;FT-0671600;K-8063;3-Amino-N-[(phenylmethoxy)carbonyl]-L-alaninemethylester;2(S)-benzyloxycarbonylamino-beta-alaninemethylesterhydrochloride;Methyl2(S)-Benzyloxycarbonylamino-3-aminopropionatehydrochloride;Methyl3-amino-(2S)-benzyloxycarbonylaminopropionatehydrochloride;Methyl3-amino-2(S)-benzyloxycarbonylaminopropionateHydrochloride;methyl3-amino-N-[(benzyloxy)carbonyl]-L-alaninatehydrochloride;(S)-Methyl3-amino-2-(((benzyloxy)carbonyl)amino)propanoatehydrochloride;3-Amino-N-[(phenylmethoxy)carbonyl]-L-alanineMethylEsterHydrochloride;methyl(2S)-3-amino-2-{[(benzyloxy)carbonyl]amino}propanoatehydrochloride;Methyl2-(S)-[N-carbobenzyloxy]amino-3-aminopropionatehydrochloride;(2S)-3-amino-2-(benzyloxycarbonylamino)propanoicacidmethylesterhydrochloride;Methyl2-(S)-[N-[(Benzyloxy)carbonyl]amino-3-aminopropionate,Hydrochloride

Chemical Name:N-alpha-Benzyloxycarbonyl-L-2,3-diaminopropionic acid methyl ester hydrochloride

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C12H17ClN2O4

M.W/Mr.

252,27*36,45 g/mole

Size

1 g;5 g;25 g;

InChI

1S/C12H16N2O4.ClH/c1-17-11(15)10(7-13)14-12(16)18-8-9-5-3-2-4-6-9;/h2-6,10H,7-8,13H2,1H3,(H,14,16);1H/t10-;/m0./s1

InChI Key

OLOFLUKZNNTGBC-PPHPATTJSA-N

Canonical SMILES

COC(=O)C(CN)NC(=O)OCC1=CC=CC=C1.Cl

1. Therapeutic potential of an intestinotrophic hormone, glucagon-like peptide 2, for treatment of type 2 short bowel syndrome rats with intestinal bacterial and fungal dysbiosis

2. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

3. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

4. C-peptide and its C-terminal fragments improve erythrocyte deformability in type 1 diabetes patients

5. High fat diet and GLP-1 drugs induce pancreatic injury in mice

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