Z-N-Me-Thr(tBu)-OH · CHA is a protected, N-methylated threonine derivative bearing a benzyloxycarbonyl (Z) carbamate on the amino group, a tert-butyl-protected side-chain hydroxyl as Thr(tBu), and a free carboxylic acid at the C-terminus. The molecule contains an N-methyl substituent that modifies the amide nitrogen's hydrogen-bonding and reactivity profile, while the tert-butyl group masks the primary alcohol functionality to reduce side reactions during peptide coupling and to control chemoselectivity. As a peptide-related intermediate, it is used in stepwise synthesis workflows to introduce a threonine residue with protected side-chain functionality, and the "· CHA" association indicates an adduct or salt form that can affect handling and solid-state properties for downstream coupling and analytical characterization.
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