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Z-Tic-OH

Z-Tic-OH is a protected, non-proteinogenic amino acid derivative featuring the Tic (Tic, tetrahydroisoquinoline-3-carboxylic acid) side-chain framework and a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality. The molecule bears a free carboxylic acid (-COOH) while the amino group is masked as a carbamate (Z), and the resulting zwitterionic character is suppressed until deprotection, with stereochemistry not specified in the provided name. Z-Tic-OH is used as a stepwise peptide synthesis building block and as a precursor for incorporating the Tic residue into peptide structures or related amino acid derivatives under conditions compatible with carbamate-protecting-group chemistry.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27483

CAS No:79261-58-8

Synonyms/Alias:Z-L-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid;79261-58-8;(3S)-2-Carbobenzoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylicAcid;(S)-2-((BENZYLOXY)CARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLICACID;(S)-N-Cbz-1,2,3,4-tetrahydroisoquinoline-3-carboxylicAcid;(S)-(+)-2-(Benzyloxycarbonyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylicacid;(S)-(+)-N-Cbz-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid;(3S)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid;Z-Tic-OH;AC1LELSU;AC1Q71AI;465054_ALDRICH;SCHEMBL3629346;CTK8E1559;ZINC57069;MolPort-001-794-613;ACN-S003042;ACT01926;EBD36874;MFCD00672545;AKOS015920142;CS22427;AJ-09564;AK-50521;AN-36622;BR-50521

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C18H17NO4
M.W/Mr.
311.34
Size
1 g;5 g;
InChI
1S/C18H17NO4/c20-17(21)16-10-14-8-4-5-9-15(14)11-19(16)18(22)23-12-13-6-2-1-3-7-13/h1-9,16H,10-12H2,(H,20,21)/t16-/m0/s1
InChI Key
YWVQGUBCAUFBCP-INIZCTEOSA-N
Canonical SMILES
C1C(N(CC2=CC=CC=C21)C(=O)OCC3=CC=CC=C3)C(=O)O

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