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  5. Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-α-MSH (4-10) amide

Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-α-MSH (4-10) amide

Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-α-MSH (4-10) amide combines multiple modifications within a cyclic framework, altering polarity, aromaticity, and backbone rigidity. Its capped and amidated termini enhance stability. The peptide supports melanocortin-binding and structural studies. Applications include peptide engineering, motif mapping, and conformational analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-α-MSH (4-10) amide(CAS 168482-23-3)

CAT No: M2715

CAS No:168482-23-3

Synonyms/Alias:Shu-9119;CHEMBL3422426;168482-23-3;(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide;SHU9119 (trifluoroacetate salt);GGYWLZFXFKFWKL-XOJVSUSESA-N;GTPL1325;BDBM50080576;AKOS024457620;FA109130;L-Lysinamide,N-acetyl-L-norleucyl-L-a-aspartyl-l-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-,(2(R)7)-lactam;N-Acetyl-L-norleucyl-L-a-aspartyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-lysinamide-(2,7) -lactam;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C54H71N15O9
M.W/Mr.
1074.2
Sequence
One Letter Code:XDHXRWK
Three Letter Code:Ac-Nle-Asp(1)-His-D-2Nal-Arg-Trp-Lys(1)-NH2
InChI
InChI=1S/C54H71N15O9/c1-3-4-15-40(63-31(2)70)48(73)69-45-27-46(71)59-21-10-9-17-39(47(55)72)64-51(76)43(25-35-28-61-38-16-8-7-14-37(35)38)67-49(74)41(18-11-22-60-54(56)57)65-50(75)42(24-32-19-20-33-12-5-6-13-34(33)23-32)66-52(77)44(68-53(45)78)26-36-29-58-30-62-36/h5-8,12-14,16,19-20,23,28-30,39-45,61H,3-4,9-11,15,17-18,21-22,24-27H2,1-2H3,(H2,55,72)(H,58,62)(H,59,71)(H,63,70)(H,64,76)(H,65,75)(H,66,77)(H,67,74)(H,68,78)(H,69,73)(H4,56,57,60)/t39-,40-,41-,42+,43-,44-,45-/m0/s1
InChI Key
GGYWLZFXFKFWKL-XOJVSUSESA-N

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