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ACT1

ACT1, a synthetic peptide designed to mimic the C-terminus of the gap junction protein connexin 43 (Cx43), with high binding specificity to the tight junction associated protein zona occludens (ZO-1).

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-146

Synonyms/Alias:alpha connexin carboxy-terminal

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C150H238N48O34
M.W/Mr.
3257.84
Sequence
RQPKIWFPNRRKPWKKRPRPDDLEI
InChI
InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11?,12-,13-,14+,15-,16+/m1/s1
InChI Key
STECJAGHUSJQJN-USLFZFAMSA-N
Isomeric SMILES
CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4

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