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ACV 1

ACV 1 is neuronal nicotinic receptor antagonist that displays selectivity for the α9α10 subtype. It can alleviates neuropathic pain in three rat models of human neuropathic pain and accelerate functional recovery of injured neurons.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R0866

CAS No:740980-24-9

Synonyms/Alias:Conotoxin Vc1.1

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C71H103N23O25S4
M.W/Mr.
1806.98
Sequence
GCCSDPRCNYDHPEIC-NH2(Disulfide bridge between Cys2 and Cys8, Cys3 and Cys16)
Labeling Target
Neuronal nicotinic receptor
Purity
>99 %
Activity
Antagonist
Solubility
-20°C
InChI
InChI=1S/C71H103N23O25S4/c1-3-32(2)55-68(117)89-44(56(74)105)27-120-122-30-47-65(114)88-43(26-95)62(111)87-42(23-54(103)104)70(119)94-18-6-8-48(94)66(115)81-36(7-4-16-78-71(75)76)57(106)90-46(29-123-121-28-45(63(112)91-47)80-51(98)24-72)64(113)84-39(21-50(73)97)60(109)83-38(19-33-10-12-35(96)13-11-33)59(108)85-40(22-53(101)102)61(110)86-41(20-34-25-77-31-79-34)69(118)93-17-5-9-49(93)67(116)82-37(58(107)92-55)14-15-52(99)100/h10-13,25,31-32,36-49,55,95-96H,3-9,14-24,26-30,72H2,1-2H3,(H2,73,97)(H2,74,105)(H,77,79)(H,80,98)(H,81,115)(H,82,116)(H,83,109)(H,84,113)(H,85,108)(H,86,110)(H,87,111)(H,88,114)(H,89,117)(H,90,106)(H,91,112)(H,92,107)(H,99,100)(H,101,102)(H,103,104)(H4,75,76,78)
InChI Key
KJQOYUHYAZGPIZ-UHFFFAOYSA-N
BoilingPoint
N/A
Melting Point
N/A

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