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Alpha-Conotoxin PIA

Alpha-Conotoxin PIA is a cysteine-rich marine peptide with a characteristic α-conotoxin fold suited for evaluating nicotinic receptor-binding motifs. Disulfide patterns stabilize its compact structure. Hydrophobic regions support membrane-associated modeling. Researchers use it in structure–function studies of conotoxin families.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Alpha-Conotoxin PIA(CAS 669050-68-4)

CAT No: R0906

CAS No:669050-68-4

Synonyms/Alias:alpha-conotoxin PIA;RDPCCSNPVC TVHNPQIC;669050-68-4;?-Conotoxin PIA;UBB05068;PD079391;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C79H125N27O25S4
M.W/Mr.
1981.3
Sequence
One Letter Code:RDPCCSNPVCXVHNPQXC
Three Letter Code:H-DL-Arg-DL-Asp-DL-Pro-DL-Cys(1)-DL-Cys(2)-DL-Ser-DL-Asn-DL-Pro-DL-Val-DL-Cys(1)-DL-xiThr-DL-Val-DL-His-DL-Asn-DL-Pro-DL-Gln-DL-xiIle-DL-Cys(2)-NH2
InChI
InChI=1S/C79H125N27O25S4/c1-8-36(6)59-74(127)96-46(61(84)114)29-132-133-30-47-66(119)95-45(28-107)65(118)94-43(25-55(83)111)77(130)106-22-12-16-52(106)71(124)100-57(34(2)3)73(126)99-49(32-135-134-31-48(67(120)97-47)98-70(123)51-15-11-21-105(51)78(131)44(26-56(112)113)92-62(115)39(80)13-9-19-88-79(85)86)68(121)103-60(37(7)108)75(128)101-58(35(4)5)72(125)91-41(23-38-27-87-33-89-38)64(117)93-42(24-54(82)110)76(129)104-20-10-14-50(104)69(122)90-40(63(116)102-59)17-18-53(81)109/h27,33-37,39-52,57-60,107-108H,8-26,28-32,80H2,1-7H3,(H2,81,109)(H2,82,110)(H2,83,111)(H2,84,114)(H,87,89)(H,90,122)(H,91,125)(H,92,115)(H,93,117)(H,94,118)(H,95,119)(H,96,127)(H,97,120)(H,98,123)(H,99,126)(H,100,124)(H,101,128)(H,102,116)(H,103,121)(H,112,113)(H4,85,86,88)
InChI Key
WINQUAHGULGZED-UHFFFAOYSA-N

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