β-Amyloid (1-9), an N-terminal fragment of beta amyloid, consists of amino acid residues 1 to 9. β-Amyloid (1-9) contains a B cell epitope, but it does not include T cell epitopes. Omission of residues 1 to 9 from the full-length Alzheimer'sβ-Amyloid peptide 1 to 40 does not prevent the peptide from forming amyloid fibrils or eliminate fibril polymorphism .
Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
M.F/Formula | C₄₂H₆₀N₁₄O₁₇ |
M.W/Mr. | 1033.01 |
Sequence | One Letter Code: DAEFRHDSG three Letter Code: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly |
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