Porcine myeloid antimicrobial peptide-23 (PMAP-23) is a host defense peptide that belongs to cathelicidins. It has potent activity against Gram-negative and Gram-positive bacteria1, and displays strong antifungal activity against yeast and mold2-3. It is not toxic to eukaryotic cells up to concentrations 100 times higher than those needed for bactericidal activity.
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.W/Mr. | 2962.8 |
Sequence | One Letter Code: RIIDLLWRVRRPQKPKFVTVWVR Three Letter Code: H-Arg-Ile-Ile-Asp-Leu-Leu-Trp-Arg-Val-Arg-Arg-Pro-Gln-Lys-Pro-Lys-Phe-Val-Thr-Val-Trp-Val-Arg-OH |
Long-term Storage Conditions | PMAP-23 antimicrobial peptide is freely soluble in H2O |
References | 1. Park K et al., Biochem. Biophys. Res. Commun. 290(1) 204-212 (2002) 2. Edwin J.A.V et al., Protein Pept Lett. 24(7),609-616 (2017) 3. Lee D.G et al., Biochem. Biophys. Res. Commun ,282 (2) 570-74 (2001) |
1. High fat diet and GLP-1 drugs induce pancreatic injury in mice
3. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
4. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry
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