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Caspase-9 Inhibitor Z-LEHD-FMK

Caspase-9 Inhibitor Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. It is applied for study of apoptosis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R0811

Synonyms/Alias:APAF-3APAF3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; Cas9; CASP9; CASP-9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; EC 3.4.22.62; ICE-LAP6CASPASE-9c; ICE-like apoptotic protease 6; MCH6apoptosis-related cysteine protease

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C32H43FN6O10
M.W/Mr.
690.7
Sequence
LEHD (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK; Glu-2 = Glu(OMe); Asp-4 = Asp(OMe))
Labeling Target
Caspase-9
Application
Blocking Reagent ; Inhibition Assay
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Activity
Inhibitor
Source#
Synthetic
Long-term Storage Conditions
Soluble in DMSO
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions
Dry, dark and at 0 - 4 °C
Solubility
-20 °C
BoilingPoint
N/A
ShelfLife
>2 years if stored properly
Melting Point
N/A

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