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Cholecystokinin Octapeptide (desulfated)

Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain, which stimulates digestion, mediates satiety, and participates in anxiety disorders. It is a cleavage product of intact CCK prohormones. The activity of CCK octapeptide (unsulfated) is 1/300 of that of sulfated CCK octapeptide.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Cholecystokinin Octapeptide (desulfated)(CAS 25679-24-7)

CAT No: 10-101-247

CAS No:25679-24-7

Synonyms/Alias:25679-24-7;H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2;Cholecystokinin Octapeptide (desulfated);CCK(26-33) Desulfated;Cholecystokinin Octapeptide, desulfated;Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2;CHEMBL216166;Desulfated CCK-8;(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid;CCK Octapeptide, desulfated;Desulfated CCK8;OIXQINQYMGNCII-YRVFCXMDSA-N;MFCD00076488;DYMGWMDF-NH2;CHEBI:138169;HY-P0196;BDBM50007921;AKOS015994633;FC108598;MS-31915;Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH(2);CS-0021290;L-Asp-L-Tyr-L-Met-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2;(3S,6S,9S,15S,18S,21S)-9-((1H-indol-3-yl)methyl)-21-amino-3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-18-(4-hydroxybenzyl)-6,15-bis(2-(methylthio)ethyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazatricosane-1,23-dioic acid;3-{2-[2-(2-{2-[2-(2-Amino-3-carboxy-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-acetylamino)-3-(1H-indol-3-yl)-propionylamino]-4-methylsulfanyl-butyrylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid;L-alpha-aspartyl-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide;

Chemical Name:(3R,6S,9S,15R,18R,21R)-9-((1H-indol-3-yl)methyl)-21-amino-3-((R)-2-hydrazinyl-3-phenylpropanamido)-18-(4-hydroxybenzyl)-6,15-bis(2-(methylthio)ethyl)-4,7,10,13,16,19,20-heptaoxo-5,8,11,14,17-pentaazatricosane-1,23-dioic acid

Custom Peptide Synthesis
cGMP Peptide
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M.F/Formula
C49H62N10O13S2
M.W/Mr.
1063.2
Sequence
One Letter Code:DYMGWMDF
Three Letter Code:H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
Application
Peptide hormone
Appearance
White or off-white lyophilized powder
Purity
98%
Activity
Non-sulfated form of the C-terminal octapeptide of CCK
Long-term Storage Conditions
Soluble to 1 mg/ml in 10% acetonitrile / water
Shipping Condition
+20°C (International: -20°C)
InChI
InChI=1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)/t32-,34-,35-,36-,37-,38-,39-/m0/s1
InChI Key
OIXQINQYMGNCII-YRVFCXMDSA-N
Canonical SMILES
O=C([C@H](CCSC)NC([C@@H](CC(O)=O)NC([C@@H](CC1=CC=CC=C1)NN)=O)=O)N[C@H](C(NCC(N[C@@H](C(N[C@@H](C(C([C@@H](CC(O)=O)N)=O)=O)CC(C=C2)=CC=C2O)=O)CCSC)=O)=O)CC3=CNC4=CC=CC=C34

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