CID 91824176 contains a peptide-like architecture with functional diversity suited for modeling molecular recognition. The arrangement of polar and hydrophobic units supports structural flexibility and solvent interactions. Researchers examine its conformational states to evaluate binding determinants. Uses span ligand screening models, sequence-function exploration, and bioorganic chemistry.
CAT No: R2628
CAS No:1801379-22-5
Synonyms/Alias:DPLG3;CHEMBL4516988;1801379-22-5;SCHEMBL18787123;EX-A9225;BDBM50554357;HY-P10030;DA-52682;CS-0904514;(2S)-N-[(2S)-3-(4-fluorophenyl)-1-(naphthalen-1-ylmethylamino)-1-oxopropan-2-yl]-N'-[(2-methylpropan-2-yl)oxy]-2-(3-phenylpropanoylamino)butanediamide;
CID 91824176, also known as 1-Deoxy-1-(dimethylamino)-D-glucitol, is a specialized carbohydrate compound distinguished by its unique structure and functional versatility. Featuring a dimethylamino group substitution on the glucitol backbone, this molecule stands out among sugar alcohol derivatives for its enhanced reactivity and potential for targeted chemical modifications. Its physicochemical properties, such as solubility and stability under various conditions, make it a valuable building block in advanced research and development settings. The compound's compatibility with a range of organic and aqueous systems further broadens its utility, enabling its integration into both small-scale laboratory protocols and larger-scale synthetic processes. Its structure allows for selective interactions and derivatizations, supporting a diverse array of scientific investigations in carbohydrate chemistry and related fields.
Synthetic Chemistry: In synthetic organic chemistry, 1-Deoxy-1-(dimethylamino)-D-glucitol serves as a versatile intermediate for constructing more complex molecules. Its primary alcohol groups and the presence of a dimethylamino moiety facilitate selective functionalization, enabling chemists to introduce additional substituents or protective groups as needed. This adaptability is particularly valuable in the synthesis of glycomimetics, where the compound can be strategically modified to mimic natural carbohydrate structures or to create novel analogs with tailored properties. The compound's reactivity profile supports both nucleophilic and electrophilic substitution reactions, making it an asset in multi-step synthetic routes aimed at generating libraries of carbohydrate-based molecules for further study.
Analytical Chemistry: In the realm of analytical chemistry, 1-Deoxy-1-(dimethylamino)-D-glucitol is utilized as a derivatization agent for enhancing the detectability of saccharides and related compounds in chromatographic analyses. Its ability to form stable conjugates with reducing sugars or other analytes improves sensitivity and selectivity in techniques such as HPLC and GC-MS. By introducing a dimethylamino group, the compound increases the volatility and ionization efficiency of target molecules, facilitating more accurate quantitation and identification in complex mixtures. Such applications are critical in fields like food science, environmental monitoring, and bioanalytical research, where precise carbohydrate profiling is essential.
Bioconjugation Research: As a functionalized carbohydrate derivative, CID 91824176 plays a significant role in bioconjugation strategies. The presence of both amino and hydroxyl functionalities allows for dual-site attachment to biomolecules, such as peptides, proteins, or nucleic acids. Researchers leverage this capability to design targeted probes, affinity tags, or immobilization platforms for use in molecular biology and diagnostics. The compound's structure supports the formation of stable linkages under mild conditions, preserving the integrity of sensitive biological substrates while enabling efficient conjugation. This makes it a preferred choice for developing custom bioconjugates in research and assay development.
Material Science: In material science, 1-Deoxy-1-(dimethylamino)-D-glucitol is explored as a functional additive or surface modifier. Its hydrophilic nature and reactive groups enable it to impart desirable properties to polymers, hydrogels, or nanomaterials. By incorporating the compound into material matrices, scientists can tailor characteristics such as solubility, biocompatibility, or surface charge, expanding the utility of these materials in applications ranging from biomedical devices to environmental sensors. The molecule's compatibility with various fabrication techniques ensures its seamless integration into next-generation material platforms.
Glycoscience Research: The unique structure of 1-Deoxy-1-(dimethylamino)-D-glucitol makes it a valuable tool in glycoscience research. Its structural similarity to naturally occurring sugar alcohols allows it to serve as a model compound for studying carbohydrate-protein interactions, enzyme mechanisms, or metabolic pathways. Researchers utilize the compound to probe the specificity of glycosyltransferases or glycosidases, advancing the understanding of carbohydrate recognition and transformation in biological systems. The ability to introduce further modifications on the dimethylamino group also supports the development of labeled or immobilized analogs for use in binding assays and structural studies, contributing to the broader field of glycobiology and molecular recognition.
2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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