Cortistatin-14 expressed in the cortex and hippocampus. Structural and functional similarities to somatostatin-14. Neuronal depressant and sleep-modulating properties in vivo. An important mediator of immunity and inflammation.
CAT# | 10-101-253 |
CAS | 186901-48-4 |
Synonyms/Alias | Endogenous neuropeptide |
M.F/Formula | C81H113N19O19S2 |
M.W/Mr. | 1721.02 |
Sequence | One Letter Code: PCKNFFWKTFSSCK (Modifications: Disulfide bonds: 2-13) Three Letter Code: Pro-Cys-Lys-Asn-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys |
Application | Cortistatin-14 may be used in competition binding assay with sst4 receptors (CHO-sst4) of CHO cells and sst1 receptors (CHO-sst1).[5] |
Appearance | White or off-white lyophilized powder |
Purity | ≥97% (HPLC) |
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