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Cortistatin-8

Cortistatin-8 features a compact peptide containing diverse residues that shape folding, binding, and conformational transitions. Aromatic and charged motifs promote structured interaction patterns. Researchers explore its stability and receptor-associated behavior. Uses include motif characterization, structural modeling, and peptide engineering.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Cortistatin-8(CAS 485803-62-1)

CAT No: R2484

CAS No:485803-62-1

Synonyms/Alias:CORTISTATIN-8;(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-16-benzyl-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-[[(2S)-pyrrolidine-2-carbonyl]amino]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide;485803-62-1;HY-P1139;AKOS024457392;PD079538;CS-0028064;(4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(4-aminobutyl)-16-benzyl-N-((S)-1,6-diamino-1-oxohexan-2-yl)-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-19-((S)-pyrrolidine-2-carboxamido)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxam;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C47H68N12O9S2
M.W/Mr.
1009.3
Sequence
One Letter Code:PCFWKTCK
Three Letter Code:H-Pro-Cys(1)-Phe-D-Trp-Lys-Thr-Cys(1)-Lys-NH2
InChI
InChI=1S/C47H68N12O9S2/c1-27(60)39-47(68)58-38(45(66)53-32(40(50)61)16-7-9-19-48)26-70-69-25-37(57-41(62)33-18-11-21-51-33)46(67)55-35(22-28-12-3-2-4-13-28)43(64)56-36(23-29-24-52-31-15-6-5-14-30(29)31)44(65)54-34(42(63)59-39)17-8-10-20-49/h2-6,12-15,24,27,32-39,51-52,60H,7-11,16-23,25-26,48-49H2,1H3,(H2,50,61)(H,53,66)(H,54,65)(H,55,67)(H,56,64)(H,57,62)(H,58,68)(H,59,63)/t27-,32+,33+,34+,35+,36-,37+,38+,39+/m1/s1
InChI Key
UHALUVNIZLPZSZ-BPBAYLLVSA-N

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