cyclo(L-Phe-L-Val) forms a compact diketopiperazine ring that exhibits notable rigidity and stability in aqueous environments. Aromatic and aliphatic residues interact to shape its hydrophobic core. The cyclic structure provides a valuable model for understanding constrained peptide folding. Research spans natural-product analogs, peptide-material scaffolds, and stereochemical studies.
CAT No: R2439
CAS No:35590-86-4
Synonyms/Alias:cyclo(L-Phe-L-Val);35590-86-4;Cyclo-(L-Val-L-Phe);(3S,6S)-3-benzyl-6-propan-2-ylpiperazine-2,5-dione;Cyclo-(L-Phe-L-Val);3S-(1-methylethyl)-6S-(phenylmethyl)-2,5-piperazinedione;(3S,6S)-3-Benzyl-6-isopropylpiperazine-2,5-dione;(3S,6S)-3-benzyl-6-(propan-2-yl)piperazine-2,5-dione;(3S,6S)-3-benzyl-6-isopropyl-piperazine-2,5-dione;CHEMBL503815;SCHEMBL25310386;CHEBI:215013;DA-72470;HY-121982;CS-0083802;
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