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[D-Tyr5]-Triptorelin

[D-Tyr5]-Triptorelin contains a D-tyrosine substitution that alters aromatic stacking and stereochemical orientation. Researchers study its receptor affinity and enhanced resistance to enzymatic degradation. Applications include analog optimization, structural analysis, and peptide-receptor interaction mapping.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: Z10-101-184

CAS No:321709-35-7

Synonyms/Alias:321709-35-7; 826-088-8; Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-D-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl-; (D-Tyr⁵,D-Trp⁶)-LHRH Trifluoroacetate; (D-Tyr⁵,D-Trp⁶)-LHRH trifluoroacetate salt; MFCD18633549; DA-59567; FT109325; Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH₂; pE-HWS(dY)(dW)LRPG-NH₂

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C66H83F3N18O15
M.W/Mr.
1425.5
Sequence
One Letter Code:XHWSYWLRPG
Three Letter Code:H-Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2.TFA
InChI
InChI=1S/C64H82N18O13.C2HF3O2/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44;3-2(4,5)1(6)7/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69);(H,6,7)/t44-,45-,46-,47+,48+,49-,50-,51-,52-;/m0./s1
InChI Key
KHNZXCLOURPVAS-USYZJHPQSA-N

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