DA-61292 offers a peptide-derived scaffold suited for exploring structural determinants of binding interactions. Its residue diversity creates a balanced hydrophobic-polar landscape. Researchers investigate conformational states across solvent systems. Applications extend to ligand optimization, sequence-function studies, and receptor-modeling research.
CAT No: R2433
CAS No:1402453-15-9
Synonyms/Alias:1402453-15-9;DA-61292;(2S)-2-acetamido-5-(diaminomethylideneamino)-N-[(2S)-2-(diethylamino)-3-(4-nitrophenyl)propanoyl]pentanamide;
DA-61292 is a synthetic small molecule compound recognized for its utility in biochemical and pharmacological research. Structurally distinct from peptides and amino acids, DA-61292 is characterized by its unique chemical scaffold, which has attracted interest for its modulatory effects on specific biological pathways. Researchers value this compound for its ability to serve as a selective probe in mechanistic studies, enabling the dissection of complex cellular processes. Its functional properties make it a valuable tool in preclinical investigations where precise modulation of target activities is required to elucidate underlying biochemical mechanisms.
Target validation: In early-stage drug discovery, DA-61292 is frequently employed to validate the role of specific molecular targets within cellular or in vitro systems. By modulating the activity of its intended target with high selectivity, the compound enables researchers to assess the biological consequences of target inhibition or activation. This approach is essential for confirming the therapeutic relevance of novel targets and can guide the prioritization of candidates for further development.
Signal transduction research: The compound's ability to influence intracellular signaling cascades makes it a powerful tool in the study of signal transduction mechanisms. Investigators utilize DA-61292 to probe the involvement of particular kinases, receptors, or downstream effectors within complex networks. Through controlled exposure in cell-based assays or biochemical reconstitution systems, the compound facilitates the mapping of pathway architecture and helps identify critical nodes susceptible to pharmacological intervention.
Chemical biology tool: As a research-use chemical probe, DA-61292 is integrated into chemical biology workflows designed to interrogate protein function and cellular phenotype. Its defined mechanism of action and bioactive profile allow for precise perturbation of target proteins, enabling structure-activity relationship studies and the exploration of off-target effects. Such investigations are instrumental in expanding understanding of protein function and the broader implications of small molecule modulation in biological systems.
High-throughput screening: DA-61292 is suitable for deployment in high-throughput screening (HTS) platforms aimed at identifying synergistic or antagonistic interactions with other chemical entities. Its well-characterized activity profile supports its use as a reference compound or positive control in assay development. Employing it in screening campaigns can enhance assay robustness, facilitate hit validation, and accelerate the identification of novel modulators with improved potency or selectivity.
Mechanistic enzymology: In the context of enzymology, DA-61292 is utilized to dissect enzyme kinetics and inhibition profiles. Through systematic application in enzyme assays, the compound aids in determining parameters such as inhibition constants, mode of action, and substrate specificity. These studies are foundational for understanding enzymatic regulation and for guiding the rational design of next-generation inhibitors or activators within the same chemical class.
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