Dulaglutide

Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C2646H4044N704O836S18
M.W/Mr.	59669.8068
Labeling Target	Glucagon-like peptide-1 (GLP-1) receptor
Application	Dulaglutide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Activity	Agonist
Biological Activity	Dulaglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist that augments glucose-dependent insulin secretion, and slows gastric emptying.
Areas of Interest	Metabolic Disease
Functions	Transmembrane signaling receptor activity
Target	GLP-1 Receptor

Long-term Storage Conditions	Soluble in DMSO
Shipping Condition	Room temperature
Organism	Human
BoilingPoint	N/A
References	Dulaglutide and liraglutide, both glucagon-like peptide-1 (GLP-1) receptor agonists, improve glycaemic control and reduce weight in patients with type 2 diabetes. In a head-to-head trial, we compared the safety and efficacy of once-weekly dulaglutide with that of once-daily liraglutide in metformin-treated patients with uncontrolled type 2 diabetes. Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): a randomised, open-label, phase 3, non-inferiority trial To compare efficacy and safety of dulaglutide, a once weekly glucagon-like peptide1 receptor agonist, to placebo and exenatide in type 2 diabetes patients. Primary objective was superiority of dulaglutide 1.5 mg versus placebo in HbA1c change at 26 weeks. Efficacy and Safety of Dulaglutide Added on to Pioglitazone and Metformin Versus Exenatide in Type 2 Diabetes in a Randomized Controlled Trial (AWARD-1)
Melting Point	N/A

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