Fexapotide Triflutate features a peptide-like structure enriched with functional diversity influencing solubility and binding interactions. Researchers investigate its conformational properties and hydrogen-bond networks. Its structural behaviors inform ligand and sequence optimization. Applications include molecular-recognition studies, structural biology, and peptide engineering.
CAT No: R2714
CAS No:1609252-56-3
Synonyms/Alias:Fexapotide triflutate;Fexapotide triflutate [USAN];UNII-98LVA678ME;98LVA678ME;NX-1207 TRIFLUOROACETATE;1609252-56-3;Fexapotide triflutate (USAN);FEXAPOTIDE TRIFLUTATE [WHO-DD];ILE-ASP-GLN-GLN-VAL-LEU-SER-ARG-ILE-LYS-LEU-GLU-ILE-LYS-ARG-CYS-LEU TRIFLUOROACETATE;L-LEUCINE, L-ISOLEUCYL-L-.ALPHA.-ASPARTYL-L-GLUTAMINYL-L-GLUTAMINYL-L-VALYL-L-LEUCYL-L-SERYL-L-ARGINYL-L-ISOLEUCYL-L-LYSYL-L-LEUCYL-L-.ALPHA.-GLUTAMYL-L-ISOLEUCYL-L-LYSYL-L-ARGINYL-L-CYSTEINYL-, 2,2,2-TRIFLUOROACETATE (1:5);L-Leucine, L-isoleucyl-L-alpha-aspartyl-L-glutaminyl-L-glutaminyl-L-valyl-L-leucyl-L-seryl-L-arginyl-L-isoleucyl-L-lysyl-L-leucyl-L-alpha-glutamyl-L-isoleucyl-L-lysyl-L-arginyl-L-cysteinyl-, 2,2,2-trifluoroacetate (1:5);CHEMBL3707309;D11248;L-isoleucyl-L-alpha-aspartyl-L-glutaminyl-L-glutaminyl-L-valyl-L-leucyl-L-seryl-L-arginyl-L-isoleucyl-L-lysyl-L-leucyl-L-alpha-glutamyl-L-isoleucyl-L-lysyl-L-arginyl-L-cysteinyl-L-leucine pentakis(2,2,2-trifluoroacetate);
Fexapotide Triflutate is a synthetic peptide compound that has garnered significant attention in biochemical research due to its unique structural features and specific biological activities. As a peptide, it is composed of a defined sequence of amino acids, which allows for precise interactions with target proteins and cellular components. Its biochemical properties make it a valuable tool for investigating peptide-mediated mechanisms and for exploring novel pathways in cellular signaling and regulatory networks. The compound's stability and defined molecular architecture also support its use in a range of experimental models, making it a versatile asset in peptide research and development.
Peptide signaling studies: Fexapotide Triflutate is widely utilized in research focused on peptide signaling pathways. Its defined sequence enables researchers to investigate receptor-ligand interactions, elucidate downstream signaling cascades, and study the modulation of cellular responses. By serving as a model peptide, it helps clarify the molecular basis of peptide-receptor binding and the subsequent biological effects, thereby advancing understanding of peptide-based cellular communication and regulatory mechanisms.
Target validation and functional assays: In the context of target validation, this synthetic peptide is employed to probe the activity of specific proteins or signaling nodes within complex biological systems. Researchers leverage its specificity to design functional assays that measure changes in cell behavior, protein phosphorylation, or gene expression following peptide exposure. These studies are instrumental in mapping the functional roles of candidate targets, optimizing experimental conditions, and validating hypotheses related to peptide-protein interactions.
Peptide synthesis optimization: Fexapotide Triflutate serves as a reference or control in the development and optimization of peptide synthesis protocols. Its well-characterized sequence and stability allow synthetic chemists to test various solid-phase or solution-phase peptide synthesis strategies, evaluate coupling efficiencies, and refine purification processes. The compound's use as a benchmark assists in troubleshooting synthetic challenges and improving overall peptide yield and quality in laboratory settings.
Biochemical pathway elucidation: The compound is also valuable for dissecting biochemical pathways involving peptide substrates or modulators. By introducing it into cell-based or in vitro systems, researchers can monitor changes in enzymatic activity, signal transduction, or metabolic flux. This approach enables detailed mapping of pathway components and interactions, providing critical insights into the regulatory architecture of peptide-influenced networks and supporting the discovery of novel pathway modulators.
Analytical method development: In analytical biochemistry, Fexapotide Triflutate is frequently used to calibrate and validate peptide detection methods, such as high-performance liquid chromatography (HPLC), mass spectrometry, or capillary electrophoresis. Its defined molecular mass and chemical stability make it an ideal standard for assessing method sensitivity, selectivity, and reproducibility. Employing this compound in method development ensures accurate quantification and reliable identification of peptides in complex biological samples, thereby supporting high-quality analytical workflows in research and industrial laboratories.
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