FR 139317 features a peptide-based architecture used to investigate ligand-receptor contact patterns. Aromatic and charged residues support complex binding interactions. Researchers examine its conformational equilibrium to interpret structure-activity relationships. Uses include receptor mapping, motif modeling, and peptide optimization.
CAT No: R2339
CAS No:142375-60-8
Synonyms/Alias:FR 139317;142375-60-8;FR139317;2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid;D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-;CHEMBL352396;(2R)-2-[[(2R)-2-[[(2S)-2-(azepane-1-carbonylamino)-4-methylpentanoyl]amino]-3-(1-methylindol-3-yl)propanoyl]amino]-3-pyridin-2-ylpropanoic acid;D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)-;(2R)-2-(((2R)-2-(((2S)-2-(azepane-1-carbonylamino)-4-methylpentanoyl)amino)-3-(1-methylindol-3-yl)propanoyl)amino)-3-pyridin-2-ylpropanoic acid;PD 147953;Tocris-1210;GTPL998;SCHEMBL2124350;DTXSID30931419;HMS3412O03;HMS3676O03;SFA37560;BDBM50286804;AKOS024456467;NCGC00025042-01;NCGC00025042-02;AS-85708;HY-102092;G78199;SR-01000597371;SR-01000597371-1;BRD-K19318328-001-01-3;Q27077729;(2R)-2-{[(2R)-2-({(2S)-2-[(1-azepanylcarbonyl)amino]-4-methylpentanoyl}amino)-3-(1-methyl-1H-indol-3-yl)propanoyl]amino}-3-(2-pyridinyl)propanoic acid;(R)-2-((R)-2-((S)-2-(azepane-1-carboxamido)-4-methylpentanamido)-3-(1-methyl-1H-indol-3-yl)propanamido)-3-(pyridin-2-yl)propanoic acid;(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-3-pyridin-2-yl-propionic acid;D-Alanine,N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-;N-{2-[(2-{[(Azepan-1-yl)(hydroxy)methylidene]amino}-1-hydroxy-4-methylpentylidene)amino]-1-hydroxy-3-(1-methyl-1H-indol-3-yl)propylidene}-3-pyridin-2-ylalanine;
1. Implications of ligand-receptor binding kinetics on GLP-1R signalling
3. Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
5. High fat diet and GLP-1 drugs induce pancreatic injury in mice
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