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Galanin (2-11) (AR-M 1896)

Galanin is a 29-aa neuropeptide with a complex role in pain processing. Galanin receptor subtypes are present in dorsal root ganglia and spinal cord with a differential distribution. Three galanin receptors, GalR1, GalR2, and GalR3, have been identified and cloned. AR-M1896 is a specific galanin R2 (GalR2) agonist.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Galanin (2-11) (AR-M 1896)(CAS 367518-31-8)

CAT No: R1888

CAS No:367518-31-8

Synonyms/Alias:WTLNSAGYLL-CONH2;367518-31-8;Galanin (2-11) porcine, rat;AR-M1896;CHEMBL578710;Galanin (2-11) amide trifluoroacetate salt;Galanin-2-11-NH..2..;Galanin(2-11)porcine,rat;Alternative Name: Gal(2-11)amide;HY-P1129;BDBM50307252;AKOS024457247;DA-63669;FG110166;CS-0028038;Galanin (2-11) porcine, rat, >=97% (HPLC), lyophilized powder;H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2; H-WTLNSAGYLL-NH2;

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M.F/Formula
C54H81N13O14
M.W/Mr.
1136.3
Sequence
One Letter Code:WTLNSAGYLL
Three Letter Code:H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2
Purity
≥97% by HPLC
Long-term Storage Conditions
Soluble to 1 mg/ml in 20% formic acid
Shipping Condition
RT, or blue ice upon request.
InChI
InChI=1S/C54H81N13O14/c1-26(2)17-37(46(57)73)62-49(76)38(18-27(3)4)63-51(78)40(20-31-13-15-33(70)16-14-31)61-44(72)24-59-47(74)29(7)60-53(80)42(25-68)66-52(79)41(22-43(56)71)64-50(77)39(19-28(5)6)65-54(81)45(30(8)69)67-48(75)35(55)21-32-23-58-36-12-10-9-11-34(32)36/h9-16,23,26-30,35,37-42,45,58,68-70H,17-22,24-25,55H2,1-8H3,(H2,56,71)(H2,57,73)(H,59,74)(H,60,80)(H,61,72)(H,62,76)(H,63,78)(H,64,77)(H,65,81)(H,66,79)(H,67,75)/t29-,30+,35-,37-,38-,39-,40-,41-,42-,45-/m0/s1
InChI Key
SUJPPMXJCZETOA-ZKEPBWIVSA-N
Canonical SMILES
CC(C)CC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC2=CNC3=CC=CC=C32)N
Isomeric SMILES
C[C@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N)O

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