γ-Glu-Cys

Substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s)

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
γ-Glu-Cys(CAS 636-58-8)

CAT No: CP27730

CAS No:636-58-8

Synonyms/Alias:gamma-glutamylcysteine;636-58-8;gamma-Glu-cys;gamma-L-glutamyl-L-cysteine;L-gamma-glutamyl-L-cysteine;L-gamma-glutamylcysteine;5-L-Glutamyl-L-cysteine;gammaGluCys;h-gamma-glu-cys-oh;Glu(-Cys);M984VJS48P;CHEBI:17515;H-|A-Glu-Cys-OH;g-L-Glutamyl-L-cysteine;(2S)-2-amino-5-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-5-oxopentanoic acid;.GAMMA.-GLUTAMYLCYSTEINE;DTXSID90212978;L-Cysteine, N-L-gamma-glutamyl-;L-CYSTEINE, L-.GAMMA.-GLUTAMYL-;(2S)-2-amino-4-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butanoic acid;3GC;gamma-L-glutamylcysteine;|A-Glu-Cys;H-GLU(CYS-OH)-OH;UNII-M984VJS48P;-Glutamylcysteine;(2S)-2-amino-4-(((1R)-1-carboxy-2-sulfanylethyl)carbamoyl)butanoic acid;des-Gly-glutathione reduced form;g-Glutamylcysteine;5-L-glutamylcysteine;Gamma-Glutamyl-Cysteine;(Des-Gly)-Glutathione;L-g-Glutamyl-L-cysteine;xN-L-g-glutamyl-Glutamine;SCHEMBL121501;xN-L-gamma-glutamyl-Glutamine;N-L-gamma-glutamyl-L-Cysteine;CHEMBL460831;DTXCID20135469;RITKHVBHSGLULN-WHFBIAKZSA-N;gamma-Glu-Cys, >=80% (HPLC);AKOS030573501;L-CYSTEINE, L-GAMMA-GLUTAMYL-;DB03408;[Gamma-glutamyl-L-cysteine]-S-conjugate;BS-52921;HY-113402;N-(1-carboxy-2-mercaptoethyl)-L-Glutamine;CS-0059333;NS00014839;C00669;C22460;E75835;Q288236;(S)-2-Amino-5-(((R)-1-carboxy-2-mercaptoethyl)amino)-5-oxopentanoic acid;(S)-2-amino-5-((R)-1-carboxy-2-mercaptoethylamino)-5-oxopentanoic acid;?-Glu-Cys; ?-Glutamylcysteine; ?-L-Glutamyl-L-cysteine; ?-L-Glutamyl-cysteine;2-Amino-5-[(1-hydroxy-1-oxo-3-sulfanylpropan-2-yl)amino]-5-oxopentanoicacid;

Chemical Name:(2S)-2-amino-5-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-5-oxopentanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C8H14N2O5S
M.W/Mr.
250.27
Sequence
One Letter Code:XC
Three Letter Code:H-gGlu-Cys-OH
Application
Di- and Tripeptides
Biological Activity
γ-Glu-Cys is produced by cleaving the Cys-Gly peptide bond of glutathione. It is also necessary for the formation of phytochelins, which are cysteine-rich thiol-reactive peptides.
Long-term Storage Conditions
≥25mg/mL in H2O, ≥52 mg/mL in DMSO, ≥54.8 mg/mL in EtOH
Shipping Condition
Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
InChI
InChI=1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1
InChI Key
RITKHVBHSGLULN-WHFBIAKZSA-N
Canonical SMILES
C(CC(=O)NC(CS)C(=O)O)C(C(=O)O)N
Isomeric SMILES
C(CC(=O)N[C@@H](CS)C(=O)O)[C@@H](C(=O)O)N
References
1. Anjum N A, Gill S S, Gill R, et al. Plant adaptation to environmental change: significance of amino acids and their derivatives. 2014.

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