Goserelin

Name: Goserelin
Brand: Creative Peptides
SKU: R2019
Availability: MadeToOrder

Goserelin, renowned for its synthetic nature, stands as a quintessential hormone deployed within the biomedicine industry, efficaciously combatting a myriad of hormone-responsive malignancies encompassing prostate and breast cancer. Its mechanism of action materializes through the tenacious inhibition of specific hormone synthesis, thus auspiciously subjugating the unbridled expansion of tumor cells while additionally alleviating consequential manifestations.

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CAT No: R2019

CAS No: 65807-02-5

Synonyms/Alias: goserelin;65807-02-5;Zoladex;Decapeptide I;Goserelina;Gosereline;Goserelinum;ICI 118630;ICI-118630;UNII-0F65R8P09N;Goserelinum [Latin];ICI 118,630;HSDB 7606;0F65R8P09N;D-Ser(t-Bu)(sup 6)aza-gly(sup 10)-GNRH;DTXSID7048297;Goserelinum (Latin);GOSERELIN (MART.);GOSERELIN [MART.];1-(5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-prolyl)semicarbazide;1233494-97-7;GOSERELIN (EP MONOGRAPH);GOSERELIN [EP MONOGRAPH];(2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(TERT-BUTOXY)-2-[(2S)-2-[(2S)-3-HYDROXY-2-[(2S)-2-[(2S)-3-(1H-IMIDAZOL-4-YL)-2-{[(2S)-5-OXOPYRROLIDIN-2-YL]FORMAMIDO}PROPANAMIDO]-3-(1H-INDOL-3-YL)PROPANAMIDO]PROPANAMIDO]-3-(4-HYDROXYPHENYL)PROPANAMIDO]PROPANAMIDO]-4-METHYLPENTANAMIDO]-5-CARBAMIMIDAMIDOPENTANOYL]-N-(CARBAMOYLAMINO)PYRROLIDINE-2-CARBOXAMIDE;(S)-N-((6S,9S,12R,15S,18S,21S,24S)-21-((1H-indol-3-yl)methyl)-1-amino-12-(tert-butoxymethyl)-6-((S)-2-(2-carbamoylhydrazine-1-carbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-18-(hydroxymethyl)-25-(1H-imidazol-4-yl)-1-imino-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-yl)-5-oxopyrrolidine-2-carboxamide;Gosereline [French];Goserelina [Spanish];MFCD01747329;Goserelin [USAN:INN:BAN];goserelin-acetate;MFCD00867894;HS-2015;ZD-9393;GOSERELIN [INN];GOSERELIN [MI];Goserelin (USAN/INN);GOSERELIN [HSDB];GOSERELIN [USAN];GOSERELIN [WHO-DD];SCHEMBL8643;CHEBI:5523;GTPL3879;CHEMBL1201247;DTXCID2028272;SCHEMBL19712239;SCHEMBL20459194;L02AE03;HMS2089D16;AKOS015994653;AKOS030213245;DB00014;NCGC00390804-01;FS110042;HY-13673;[D-Ser(tBu)6,Azagly10]-LHRH acetate salt;NS00120430;(D-Ser(tBu)6,Azagly10)-LHRH (free base);D04405;AB01275466-01;EN300-7480905;Q1992653;BRD-K99504665-001-01-2;6-(O-(1,1-Dimethylethyl)-D-serine)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide;

Chemical Name: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C59H84N18O14
M.W/Mr.	1269.4
Sequence	One Letter Code:XHWSYXLRP Three Letter Code:H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2

InChI	InChI=1S/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90)/t38-,39-,40-,41-,42-,43-,44-,45+,46-/m0/s1
InChI Key	BLCLNMBMMGCOAS-URPVMXJPSA-N
Canonical SMILES	CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NNC(=O)N)NC(=O)C(COC(C)(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
Isomeric SMILES	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NNC(=O)N)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6

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