Goserelin, renowned for its synthetic nature, stands as a quintessential hormone deployed within the biomedicine industry, efficaciously combatting a myriad of hormone-responsive malignancies encompassing prostate and breast cancer. Its mechanism of action materializes through the tenacious inhibition of specific hormone synthesis, thus auspiciously subjugating the unbridled expansion of tumor cells while additionally alleviating consequential manifestations.
CAT No: R2019
CAS No: 65807-02-5
Synonyms/Alias: goserelin;65807-02-5;Zoladex;Decapeptide I;Goserelina;Gosereline;Goserelinum;ICI 118630;ICI-118630;UNII-0F65R8P09N;Goserelinum [Latin];ICI 118,630;HSDB 7606;0F65R8P09N;D-Ser(t-Bu)(sup 6)aza-gly(sup 10)-GNRH;DTXSID7048297;Goserelinum (Latin);GOSERELIN (MART.);GOSERELIN [MART.];1-(5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-prolyl)semicarbazide;1233494-97-7;GOSERELIN (EP MONOGRAPH);GOSERELIN [EP MONOGRAPH];(2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(TERT-BUTOXY)-2-[(2S)-2-[(2S)-3-HYDROXY-2-[(2S)-2-[(2S)-3-(1H-IMIDAZOL-4-YL)-2-{[(2S)-5-OXOPYRROLIDIN-2-YL]FORMAMIDO}PROPANAMIDO]-3-(1H-INDOL-3-YL)PROPANAMIDO]PROPANAMIDO]-3-(4-HYDROXYPHENYL)PROPANAMIDO]PROPANAMIDO]-4-METHYLPENTANAMIDO]-5-CARBAMIMIDAMIDOPENTANOYL]-N-(CARBAMOYLAMINO)PYRROLIDINE-2-CARBOXAMIDE;(S)-N-((6S,9S,12R,15S,18S,21S,24S)-21-((1H-indol-3-yl)methyl)-1-amino-12-(tert-butoxymethyl)-6-((S)-2-(2-carbamoylhydrazine-1-carbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-18-(hydroxymethyl)-25-(1H-imidazol-4-yl)-1-imino-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-yl)-5-oxopyrrolidine-2-carboxamide;Gosereline [French];Goserelina [Spanish];MFCD01747329;Goserelin [USAN:INN:BAN];goserelin-acetate;MFCD00867894;HS-2015;ZD-9393;GOSERELIN [INN];GOSERELIN [MI];Goserelin (USAN/INN);GOSERELIN [HSDB];GOSERELIN [USAN];GOSERELIN [WHO-DD];SCHEMBL8643;CHEBI:5523;GTPL3879;CHEMBL1201247;DTXCID2028272;SCHEMBL19712239;SCHEMBL20459194;L02AE03;HMS2089D16;AKOS015994653;AKOS030213245;DB00014;NCGC00390804-01;FS110042;HY-13673;[D-Ser(tBu)6,Azagly10]-LHRH acetate salt;NS00120430;(D-Ser(tBu)6,Azagly10)-LHRH (free base);D04405;AB01275466-01;EN300-7480905;Q1992653;BRD-K99504665-001-01-2;6-(O-(1,1-Dimethylethyl)-D-serine)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide;
Chemical Name: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Quick InquiryCustom Peptide SynthesisPeptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.F/Formula | C59H84N18O14 |
M.W/Mr. | 1269.4 |
Sequence | One Letter Code:XHWSYXLRP Three Letter Code:H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2 |
InChI | InChI=1S/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90)/t38-,39-,40-,41-,42-,43-,44-,45+,46-/m0/s1 |
InChI Key | BLCLNMBMMGCOAS-URPVMXJPSA-N |
Canonical SMILES | CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NNC(=O)N)NC(=O)C(COC(C)(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 |
Isomeric SMILES | CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NNC(=O)N)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6 |
1. Cationic cell-penetrating peptides are potent furin inhibitors
2. Myotropic activity of allatostatins in tenebrionid beetles
4. The spatiotemporal control of signalling and trafficking of the GLP-1R
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at info@creative-peptides.com. We will endeavor to provide highly satisfying products and services.