H-Arg-Arg-Arg-Arg-Arg-Arg-OH is a highly cationic hexapeptide rich in guanidinium groups, frequently used to model nucleic-acid and membrane interactions. Strong electrostatics drive association with anionic biomolecules. Researchers probe its role in cell-penetrating and condensation-like behavior in vitro. Applications include polycation research, peptide-DNA binding studies, and electrostatic-assembly modeling.
CAT No: R2367
CAS No:96337-25-6
Synonyms/Alias:H-Arg-Arg-Arg-Arg-Arg-Arg-OH;Hexaarginine;96337-25-6;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid;CHEMBL2049164;Arg-Arg-Arg-Arg-Arg-Arg;BDBM50387012;DA-74101;FA109316;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoic acid;
1. Cationic cell-penetrating peptides are potent furin inhibitors
2. TMEM16F and dynamins control expansive plasma membrane reservoirs
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