H-Gly-Phe-AMC

H-Gly-Phe-AMC is a fluorogenic dipeptide substrate with an AMC reporter for monitoring protease activity. The Gly-Phe motif presents a hydrophobic cleavage site recognized by chymotrypsin-like enzymes. Researchers quantify fluorescence release to assess catalytic rates. Applications include enzyme-assay design, inhibitor screening, and substrate optimization.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
H-Gly-Phe-AMC(CAS 201852-70-2)

CAT No: R2403

CAS No:201852-70-2

Synonyms/Alias:H-Gly-Phe-AMC;201852-70-2;Gly-Phe-AMC;L-Phenylalaninamide, glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;(2S)-2-[(2-aminoacetyl)amino]-N-(4-methyl-2-oxochromen-7-yl)-3-phenylpropanamide;MFCD00152091;DTXSID60426782;HY-P4425;DA-74146;FG110504;CS-0654071;(2S)-2-(2-AMINOACETAMIDO)-N-(4-METHYL-2-OXOCHROMEN-7-YL)-3-PHENYLPROPANAMIDE;(S)-2-(2-Aminoacetamido)-N-(4-methyl-2-oxo-2H-chromen-7-yl)-3-phenylpropanamide;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C21H21N3O4
M.W/Mr.
379.4
Sequence
One Letter Code:GF
Three Letter Code:H-Gly-Phe-AMC
InChI
InChI=1S/C21H21N3O4/c1-13-9-20(26)28-18-11-15(7-8-16(13)18)23-21(27)17(24-19(25)12-22)10-14-5-3-2-4-6-14/h2-9,11,17H,10,12,22H2,1H3,(H,23,27)(H,24,25)/t17-/m0/s1
InChI Key
OXYDLMUFQZNZMD-KRWDZBQOSA-N

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