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H-Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-NHEt.TFA

H-Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-NHEt·TFA carries pyroglutamate, D-residues, and an N-ethylamide terminus to tune stability and receptor interaction. Aromatic side chains contribute to π-stacking and spectroscopic signals. Researchers evaluate its conformational ensemble and proteolytic resistance. Applications include analog-optimization work, receptor-binding investigations, and neuropeptide-mimetic studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
H-Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-NHEt.TFA(CAS 1426173-46-7)

CAT No: R2584

CAS No:1426173-46-7

Synonyms/Alias:1426173-46-7;H-Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-NHEt.TFA;FD109428;(Des-Gly10,D-Tyr5,D-Trp6,Pro-NHEt 9)-LHRH trifluoroacetate salt;Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-NHEt; pE-HWS(dY)(dW)LRP-NHEt;

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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C66H84F3N17O14
M.W/Mr.
1396.5
Sequence
One Letter Code:XHWSYWLRP
Three Letter Code:H-Pyr-His-Trp-Ser-D-Tyr-D-Trp-Leu-Arg-Pro-NHEt.TFA
InChI
InChI=1S/C64H83N17O12.C2HF3O2/c1-4-68-62(92)53-16-10-24-81(53)63(93)46(15-9-23-69-64(65)66)74-56(86)47(25-35(2)3)75-58(88)49(27-37-30-70-43-13-7-5-11-41(37)43)77-57(87)48(26-36-17-19-40(83)20-18-36)76-61(91)52(33-82)80-59(89)50(28-38-31-71-44-14-8-6-12-42(38)44)78-60(90)51(29-39-32-67-34-72-39)79-55(85)45-21-22-54(84)73-45;3-2(4,5)1(6)7/h5-8,11-14,17-20,30-32,34-35,45-53,70-71,82-83H,4,9-10,15-16,21-29,33H2,1-3H3,(H,67,72)(H,68,92)(H,73,84)(H,74,86)(H,75,88)(H,76,91)(H,77,87)(H,78,90)(H,79,85)(H,80,89)(H4,65,66,69);(H,6,7)/t45-,46-,47-,48+,49+,50-,51-,52-,53-;/m0./s1
InChI Key
MQSBDALSNXYZTH-WUTRMYCASA-N

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