KK14(R)

KK14(R) is a Lys-rich peptide variant designed to provide a highly cationic environment along the chain. Positive charges favor interaction with anionic membranes, nucleic acids, or acidic protein surfaces. Researchers analyze its secondary structure and aggregation tendencies in different solvents. Applications include cell-penetrating motif studies, complex coacervate modeling, and charge-driven assembly research.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R2727

Synonyms/Alias:KK14(R); HY-P10329; CS-1051158.

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C96H138N26O14
M.W/Mr.
1880.3
Sequence
One Letter Code:KKFFRAWWAPRFLK
Three Letter Code:H-Lys-Lys-Phe-Phe-Arg-Ala-Trp-Trp-Ala-Pro-Arg-Phe-Leu-Lys-NH2
InChI
InChI=1S/C96H138N26O14/c1-57(2)49-74(88(130)112-70(81(101)123)38-19-22-44-98)117-90(132)76(51-61-29-10-6-11-30-61)119-86(128)73(41-25-47-107-96(104)105)115-93(135)80-42-26-48-122(80)94(136)59(4)111-87(129)78(53-63-55-108-68-36-16-14-33-65(63)68)121-92(134)79(54-64-56-109-69-37-17-15-34-66(64)69)116-82(124)58(3)110-84(126)72(40-24-46-106-95(102)103)114-89(131)75(50-60-27-8-5-9-28-60)120-91(133)77(52-62-31-12-7-13-32-62)118-85(127)71(39-20-23-45-99)113-83(125)67(100)35-18-21-43-97/h5-17,27-34,36-37,55-59,67,70-80,108-109H,18-26,35,38-54,97-100H2,1-4H3,(H2,101,123)(H,110,126)(H,111,129)(H,112,130)(H,113,125)(H,114,131)(H,115,135)(H,116,124)(H,117,132)(H,118,127)(H,119,128)(H,120,133)(H,121,134)(H4,102,103,106)(H4,104,105,107)/t58-,59-,67-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-/m0/s1
InChI Key
VJHRZHBBVXVBOK-DRNPRWLXSA-N

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