Lonodelestat

Lonodelestat is a peptide analog constructed from aromatic, hydrophobic, and polar residues arranged to promote structured folding and surface interactions. Researchers use it to examine ligand-protein binding, secondary-structure transitions, and conformational energetics. Its balanced composition suits advanced biophysical analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Lonodelestat(CAS 906547-89-5)

CAT No: R2420

CAS No:906547-89-5

Synonyms/Alias:Lonodelestat;Lonodelestat [INN];5SD2VOV3MF;906547-89-5;UNII-5SD2VOV3MF;POL6014;1,13-Anhydro(L-alanyl-L-seryl-L-isoleucyl-L-prolyl-lprolyl-L-glutaminyl-L-lysyl-L-tyrosyl-D-prolyl-L-prolyl-(2S)-2-aminodecanoyl-L-alpha-glutamyl-L-threonine);Cyclo(L-alanyl-L-seryl-L-isoleucyl-L-prolyl-L-prolyl-L-glutaminyl-L-lysyl-L-tyrosyl-D-prolyl-L-prolyl-(2S)-2-aminodecanoyl-L-alpha-glutamyl-L-threonyl);cyclo[Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-D-Pro-Pro-Nle(Bu)-Glu-Thr];1,13-ANHYDRO(L-ALANYL-L-SERYL-L-ISOLEUCYL-L-PROLYL-LPROLYL-L-GLUTAMINYL-L-LYSYL-L-TYROSYL-D-PROLYL-L-PROLYL-(2S)-2-AMINODECANOYL-L-.ALPHA.-GLUTAMYL-L-THREONINE);CYCLO(L-ALANYL-L-SERYL-L-ISOLEUCYL-L-PROLYL-L-PROLYL-L-GLUTAMINYL-L-LYSYL-L-TYROSYL-D-PROLYL-L-PROLYL-(2S)-2-AMINODECANOYL-L-.ALPHA.-GLUTAMYL-L-THREONYL);cyclo(Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-D-Pro-Pro-Nle(Bu)-Glu-Thr);GTPL11275;HY-P3293;POL-6014;AKOS040758444;DA-65052;CS-0204184;Cyclo[L-alanyl-L-seryl-L-isoleucyl-L-prolyl-L-prolyl-L-glutaminyl-L-lysyl-L-tyrosyl-D-prolyl-L-prolyl-(2S)-2-aminodecanoyl-L-alpha-glutamyl-L-threonyl] (9CI);

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C71H111N15O19
M.W/Mr.
1478.7
Sequence
Three Letter Code:cyclo[Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-D-Pro-Pro-Nle(Bu)(Bu)-Glu-Thr]
InChI
InChI=1S/C71H111N15O19/c1-6-8-9-10-11-12-19-46-60(94)76-48(30-32-56(91)92)63(97)82-58(42(5)88)67(101)74-41(4)59(93)80-50(39-87)64(98)81-57(40(3)7-2)71(105)86-37-18-24-54(86)70(104)84-35-16-22-52(84)66(100)78-47(29-31-55(73)90)62(96)75-45(20-13-14-33-72)61(95)79-49(38-43-25-27-44(89)28-26-43)68(102)85-36-17-23-53(85)69(103)83-34-15-21-51(83)65(99)77-46/h25-28,40-42,45-54,57-58,87-89H,6-24,29-39,72H2,1-5H3,(H2,73,90)(H,74,101)(H,75,96)(H,76,94)(H,77,99)(H,78,100)(H,79,95)(H,80,93)(H,81,98)(H,82,97)(H,91,92)/t40-,41-,42+,45-,46-,47-,48-,49-,50-,51-,52-,53+,54-,57-,58-/m0/s1
InChI Key
JMWYNUHGKFJVIB-QGFXQWJDSA-N

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