LPYFD-NH2

LPYFD-NH2 is a neuroprotective peptide that binds to amyloid beta (Aβ) and protects neurons against toxic effects of Aβ (1-42) in vitro and in vivo.

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CAT#	R0821
CAS	700361-48-4
M.F/Formula	C33H44N6O8
M.W/Mr.	652.75
Sequence	LPYFD-NH2(Modifications: Asp-5 = C-terminal amide)
Labeling Target	Amyloid beta (Aβ)
Application	Neuroprotective peptide that binds to amyloid beta (Aβ). Protects neurons against toxic effects of Aβ (1-42) in vitro and in vivo. Potential therapeutic in the treatment of Alzheimer's Disease.

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Storage	-20°C
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C33H44N6O8/c1-19(2)15-23(34)33(47)39-14-6-9-27(39)32(46)38-26(17-21-10-12-22(40)13-11-21)31(45)37-25(16-20-7-4-3-5-8-20)30(44)36-24(29(35)43)18-28(41)42/h3-5,7-8,10-13,19,23-27,40H,6,9,14-18,34H2,1-2H3,(H2,35,43)(H,36,44)(H,37,45)(H,38,46)(H,41,42)/t23-,24-,25-,26-,27-/m0/s1
InChI Key	IZXBZWOUOODINS-IRGGMKSGSA-N
Isomeric SMILES	CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC(=O)O)C(=O)N)N
BoilingPoint	N/A
Melting Point	N/A