N-Formyl-Met-Leu-Phe

Name: N-Formyl-Met-Leu-Phe
Brand: Creative Peptides
SKU: R1553
Availability: MadeToOrder

N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1553

CAS No:59880-97-6

Synonyms/Alias:N-Formyl-Met-Leu-Phe;59880-97-6;FMLP;Chemotactic peptide;fMLF;F-Met-leu-phe;N-Formyl-methionyl-leucyl-phenylalanine;fMetLeuPhe;fMet-Leu-Phe;N-Formyl-L-methionyl-L-leucyl-L-phenylalanine;formyl-Met-Leu-Phe;N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE;(S)-2-((S)-2-((S)-2-Formamido-4-(methylthio)butanamido)-4-methylpentanamido)-3-phenylpropanoic acid;MFCD00036780;CHEMBL267179;CHEBI:53490;(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid;N-Formyl-MLF;fMLP;N-Formyl-MLF;SMR000857394;LO6AVJ8RCE;Formyl-Met-Leu-Phe-OH;fMLP (misnomer but widely used);NSC-350593;L-Phenylalanine, N-formyl-L-methionyl-L-leucyl-;(2S)-2-(((2S)-2-(((2S)-2-FORMAMIDO-4-METHYLSULFANYLBUTANOYL)AMINO)-4-METHYLPENTANOYL)AMINO)-3-PHENYLPROPANOIC ACID;Formyl met leu phe;Chemotactic peptide?;SCHEMBL39529;MLS001361389;MLS002207097;GTPL1022;DTXSID9041077;GLXC-10556;GLXC-26059;HMS2235B23;HY-P0224;formyl-methionyl-leucyl-phenylalanine;BDBM50050937;F-MET-LEU-PHE L-PHENYLALANINE;AKOS024456858;CS-6489;n-formylmethionine-leucine-phenylalanine;AS-57764;N-Formyl-Met-Leu-Phe, >=97% (HPLC);F1158;D90695;N-(N-(N-FORMYL-L-METHIONYL)-L-LEUCYL);Formyl-Met-Leu-Phe-OH - CAS 59880-97-6;Chemotactic Peptide (For-L-Met-L-Leu-L-Phe-OH);N-Formyl-Met-Leu-Phe, BioXtra, >=99.0% (TLC);Q5090627;(2S)-2-[(2S)-2-[(2S)-2-formamido-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-3-phenylpropanoic acid;(S)-2-((S)-2-((S)-2-Formamido-4-(methylthio)butanamido)-4-methylpentanamido)-3-phenylpropanoicacid;(S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid;

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C21H31N3O5S

M.W/Mr.

437.6

Sequence

One Letter Code:MLF
Three Letter Code:For-Met-Leu-Phe-OH

Purity

≥98%

Long-term Storage Conditions

Soluble to 4.38 mg/ml in DMSO

Shipping Condition

Shipped at room temperature

InChI

InChI=1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

InChI Key

PRQROPMIIGLWRP-BZSNNMDCSA-N

Canonical SMILES

O=C(O)[C@@H](N([H])C([C@@H](N(C([C@@H](N(C=O)[H])CCSC)=O)[H])CC(C)C)=O)CC1=CC=CC=C1

1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

2. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency

3. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

4. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

5. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die

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