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N-δ-Trityl-L-glutamine

N-δ-Trityl-L-glutamine is a protected amino acid derivative belonging to the glutamine family, featuring the glutamyl side chain with an amide terminus while the α-amino group and α-carboxyl group are present as an amino acid framework. The N-δ-trityl substituent on the δ-nitrogen of the side-chain amide introduces a trityl (Trt) protecting group that masks the side-chain nucleophile and provides chemoselectivity during peptide-coupling steps, with the L stereochemistry indicated by the product name. This protected glutamine analogue is used as a building block in peptide synthesis and related derivatization workflows where controlled exposure of the side-chain amide functionality is required for stepwise assembly and subsequent deprotection.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00823

CAS No:102747-84-2

Synonyms/Alias:H-Gln(Trt)-OH;102747-84-2;N'-Trityl-L-glutamine;(S)-2-Amino-5-oxo-5-(tritylamino)pentanoicacid;(2S)-2-amino-5-oxo-5-(tritylamino)pentanoicacid;AmbotzHAA6660;AC1OLRAW;H-Gln(Trt)-OH.H2O;N-|A-Trityl-L-glutamine;SCHEMBL7850584;CTK3J1672;MolPort-003-981-812;H-Gln(Trt)-2-ChlorotritylResin;ZINC4899661;ANW-59248;AKOS015923027;AKOS015962852;AM81780;AN-7772;RTR-000655;AC-19199;AJ-52578;AK-41205;ST24036011;V1062

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M.F/Formula
C24H24N2O3
M.W/Mr.
388.5
Abbr
H-Gln(Trt)-OH
InChI
1S/C24H24N2O3/c25-21(23(28)29)16-17-22(27)26-24(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17,25H2,(H,26,27)(H,28,29)/t21-/m0/s1
InChI Key
XIFFJPJZPDCOJH-NRFANRHFSA-N
Canonical SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CCC(C(=O)O)N

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