Nangibotide

Name: Nangibotide
Brand: Creative Peptides
SKU: R2070
Availability: MadeToOrder

Nangibotide is an inhibitor of TREM-1, a receptor found on certain white blood cells.

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CAT No: R2070

CAS No: 2014384-91-7

Synonyms/Alias: Nangibotide;2014384-91-7;nangibotidum;Nangibotida;DTXSID201336482;Motrem;NANGIBOTIDE [INN];59HD7BLX9H;NANGIBOTIDE [WHO-DD];DTXCID101766688;Lissamine-rhodamine dodecanoic acid;LR 12;LR-12;DA-65927;Leu-Gln-Glu-Glu-Asp-Ala-Gly-Glu-Tyr-Gly-Cys-Met-NH2;L-METHIONINAMIDE, L-LEUCYL-L-GLUTAMINYL-L-.ALPHA.-GLUTAMYL-L-.ALPHA.-GLUTAMYL-L-.ALPHA.-ASPARTYL-L-ALANYLGLYCYL-L-.ALPHA.-GLUTAMYL-L-TYROSYLGLYCYL-L-CYSTEINYL-;L-Methioninamide, L-leucyl-L-glutaminyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanylglycyl-L-alpha-glutamyl-L-tyrosylglycyl-L-cysteinyl-;

Chemical Name: (4S)-4-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]acetyl]amino]-5-[[(2S)-1-[[2-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C54H83N15O21S2
M.W/Mr.	1342.5
Sequence	One Letter Code:LQQEDAGEYGCM Three Letter Code:H-Leu-Gln-Gln-Glu-Asp-Ala-Gly-Glu-Tyr-Gly-Cys-Met-NH2

InChI	InChI=1S/C54H83N15O21S2/c1-25(2)19-29(55)47(83)65-32(9-13-38(56)71)50(86)66-33(10-14-39(57)72)51(87)67-34(12-16-43(77)78)52(88)69-36(21-44(79)80)53(89)61-26(3)46(82)59-22-40(73)62-31(11-15-42(75)76)49(85)68-35(20-27-5-7-28(70)8-6-27)48(84)60-23-41(74)63-37(24-91)54(90)64-30(45(58)81)17-18-92-4/h5-8,25-26,29-37,70,91H,9-24,55H2,1-4H3,(H2,56,71)(H2,57,72)(H2,58,81)(H,59,82)(H,60,84)(H,61,89)(H,62,73)(H,63,74)(H,64,90)(H,65,83)(H,66,86)(H,67,87)(H,68,85)(H,69,88)(H,75,76)(H,77,78)(H,79,80)/t26-,29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1
InChI Key	JLOOQDWHNKOITN-DAHMAOPXSA-N
Canonical SMILES	CC(C)CC(C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NCC(=O)NC(CS)C(=O)NC(CCSC)C(=O)N)N
Isomeric SMILES	C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)N

1. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

2. Cationic cell-penetrating peptides are potent furin inhibitors

3. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

4. cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

5. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

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