Nelipepimut-S

Name: Nelipepimut-S
Brand: Creative Peptides
SKU: R2072
Availability: MadeToOrder

Nelipepimut-S, an advanced peptide-based immunotherapeutic intervention, has demonstrated significant efficacy within the biomedical sector as it pertains to breast cancer management. Acting with precision, it selectively engages HER2-positive malignancies, thereby amplifying and fortifying the immune system's retaliation against these deleterious cells.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: R2072

CAS No: 160212-35-1

Synonyms/Alias: NELIPEPIMUT-S;Neuvax;160212-35-1;NeuVax vaccine;KIFGSLAFL;Nelipepimut-S [USAN];E75 peptide;UNII-7M0A29CD8B;7M0A29CD8B;DTXSID80166835;L-Leucine, L-lysyl-L-isoleucyl-L-phenylalanylglycyl-L-seryl-L-leucyl-L-alanyl-L-phenylalanyl-;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid;Nelipepimut-S (USAN);L-lysyl-L-isoleucyl-L-phenylalanylglycyl-L-seryl-L-leucyl-L-alanyl-L-phenylalanyl-L-leucine;Human receptor tyrosine-protein kinase erbB-2 (proto-oncogene Neu, tyrosine kinase- type cell surface receptor HER2, CD340)-(347-355)-peptide;Nelipepimut s;E75 HER2 peptide;E-75 PEPTIDE;10: PN: WO2015050181 SEQID: 10 claimed protein;CHEMBL386200;NELIPEPIMUT S [WHO-DD];DTXCID3089326;AHOKKYCUWBLDST-QYULHYBRSA-N;CHEBI:230310;Her2 369-377;BDBM50409332;AKOS040753235;DA-76075;E-75;HER-2/NEU PEPTIDE (369-377);HY-106204;CS-0025241;Q27268544;HUMAN RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (PROTO-ONCOGENE NEU, TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER2, CD340)-(347-355)-PEPTIDE;

Chemical Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C50H78N10O11
M.W/Mr.	995.2
Sequence	One Letter Code:KIFGSLAFL Three Letter Code:H-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH

InChI	InChI=1S/C50H78N10O11/c1-8-31(6)42(60-44(64)35(52)21-15-16-22-51)49(69)58-37(25-33-17-11-9-12-18-33)45(65)53-27-41(62)55-40(28-61)48(68)57-36(23-29(2)3)46(66)54-32(7)43(63)56-38(26-34-19-13-10-14-20-34)47(67)59-39(50(70)71)24-30(4)5/h9-14,17-20,29-32,35-40,42,61H,8,15-16,21-28,51-52H2,1-7H3,(H,53,65)(H,54,66)(H,55,62)(H,56,63)(H,57,68)(H,58,69)(H,59,67)(H,60,64)(H,70,71)/t31-,32-,35-,36-,37-,38-,39-,40-,42-/m0/s1
InChI Key	AHOKKYCUWBLDST-QYULHYBRSA-N
Canonical SMILES	CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CCCCN)N
Isomeric SMILES	CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](CCCCN)N

2. TMEM16F and dynamins control expansive plasma membrane reservoirs

3. Glucagonlike peptide 2 analogue teduglutide: stimulation of proliferation but reduction of differentiation in human Caco-2 intestinal epithelial cells

4. Sex differences in oxidative stress level and antioxidative enzymes expression and activity in obese pre-diabetic elderly rats treated with metformin or liraglutide

5. Therapeutic potential of an intestinotrophic hormone, glucagon-like peptide 2, for treatment of type 2 short bowel syndrome rats with intestinal bacterial and fungal dysbiosis

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