Octapeptide-2 is a synthetic peptide composed of eight amino acids, designed for use as an active ingredient in cosmetic formulations. Recognized for its biomimetic properties, Octapeptide-2 supports the appearance of smoother and more even skin by helping to optimize skin condition. Its stability and compatibility make it suitable for a range of topical applications, including serums, creams, and emulsions intended for facial care products.
CAT No: 10-101-220
CAS No:1374396-34-5
Synonyms/Alias:Octapeptide 2; 1374396-34-5; EX-A6261; HY-P5253; CS-0863864; (4S)-4-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]propanoyl]amino]-5-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Mechanism of Action (MOA)
Octapeptide-2 is a synthetic signaling peptide that interacts with cellular communication pathways in the skin. By mimicking naturally occurring peptide sequences, it is suggested to modulate key biochemical processes involved in cell-to-cell signaling. This peptide may influence the activity of specific skin receptors, supporting the regulation of cellular functions such as protein synthesis and cellular communication, which are important for maintaining the appearance and resilience of the skin.
Octapeptide-2 is suitable for incorporation into a variety of cosmetic formulations.
- Recommended for use in facial serums and creams- Can be added to eye contour products- Compatible with lightweight lotions and emulsions- Suitable for leave-on skin care formulations- May be included in sheet masks and gel-based treatments- Suggested use levels typically range from 0.1% to 2%
2. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
4. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
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