Octapeptide-2

Octapeptide-2 is a synthetic peptide composed of eight amino acids, designed for use as an active ingredient in cosmetic formulations. Recognized for its biomimetic properties, Octapeptide-2 supports the appearance of smoother and more even skin by helping to optimize skin condition. Its stability and compatibility make it suitable for a range of topical applications, including serums, creams, and emulsions intended for facial care products.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-220

CAS No:1374396-34-5

Synonyms/Alias:Octapeptide 2; 1374396-34-5; EX-A6261; HY-P5253; CS-0863864; (4S)-4-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]propanoyl]amino]-5-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

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  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing

Mechanism of Action (MOA)

Octapeptide-2 is a synthetic signaling peptide that interacts with cellular communication pathways in the skin. By mimicking naturally occurring peptide sequences, it is suggested to modulate key biochemical processes involved in cell-to-cell signaling. This peptide may influence the activity of specific skin receptors, supporting the regulation of cellular functions such as protein synthesis and cellular communication, which are important for maintaining the appearance and resilience of the skin.

Octapeptide-2 is suitable for incorporation into a variety of cosmetic formulations.

- Recommended for use in facial serums and creams
- Can be added to eye contour products
- Compatible with lightweight lotions and emulsions
- Suitable for leave-on skin care formulations
- May be included in sheet masks and gel-based treatments
- Suggested use levels typically range from 0.1% to 2%

Shipping Condition
Room temperature in continental US; may vary elsewhere.

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