Palmitoyl Tripeptide-28 is a synthetic peptide composed of three amino acids linked to a palmitic acid chain, facilitating enhanced skin penetration. Widely utilized in cosmetic formulations, this peptide is valued for its role in supporting the skin's extracellular matrix and improving skin texture. Palmitoyl Tripeptide-28 is compatible with a range of topical applications, including emulsions, serums, and gels, and is suitable for use in global cosmetic markets.
CAT No: CPC1752
Mechanism of Action (MOA)
Palmitoyl Tripeptide-28 is a synthetic signal peptide designed to mimic sequences found in extracellular matrix proteins. It interacts with skin cells by modulating cellular signaling pathways involved in collagen synthesis, particularly through the upregulation of key matrix components via TGF-β (Transforming Growth Factor Beta) pathways. This peptide may support the maintenance of skin structure by encouraging optimal extracellular matrix protein expression, contributing to the visible appearance of skin smoothness and resilience.
Palmitoyl Tripeptide-28 is suitable for incorporation into a variety of cosmetic formulations targeting skin care.
- Recommended for use in facial serums and creams- Compatible with emulsions, gels, and lotion bases- Can be added to eye contour products- Suitable for daily leave-on treatments- Appropriate for both day and night skincare routines- May be included in sheet masks and ampoules
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
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