PDC31 represents a defined peptide construct studied for its structural determinants and receptor-interacting potential. Its side-chain arrangement influences folding, charge distribution, and molecular recognition. Researchers examine its conformational preferences across varied environments. Applications include ligand modeling, peptide engineering, and synthetic optimization.
CAT No: R2443
CAS No:634586-40-6
Synonyms/Alias:CHEMBL1910324;PDC31;634586-40-6;BDBM50355549;(2R)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-[[2-[[(2R)-2-[[(2R,3R)-2-amino-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoic acid;
PDC31 is a synthetic peptide compound recognized for its distinctive sequence and structural properties, which make it a valuable tool in a range of peptide-based research applications. As a member of the peptide class, it offers unique opportunities for investigating molecular interactions, structure-activity relationships, and functional modulation within biological systems. Researchers utilize such synthetic peptides to probe cellular pathways, develop new assay systems, and design innovative biomolecular tools. The versatility of PDC31 stems from its customizable nature, enabling precise manipulation for targeted scientific inquiries within biochemistry, molecular biology, and pharmaceutical research.
Peptide structure-activity studies: PDC31 serves as an essential reagent in elucidating the relationship between peptide sequence, conformation, and biological activity. By incorporating this synthetic peptide into experimental models, researchers can systematically modify amino acid residues to assess their impact on receptor binding, enzymatic recognition, or protein-protein interactions. Such studies provide fundamental insights into the molecular determinants of specificity and affinity, supporting the rational design of more effective peptide analogues and mimetics in both basic and applied research settings.
Receptor binding assays: In receptor pharmacology and cell signaling research, PDC31 is frequently employed as a ligand or competitor in binding assays. Its defined sequence enables the exploration of ligand-receptor interactions, affinity constants, and selectivity profiles. Utilizing this peptide in radioligand displacement, fluorescence polarization, or surface plasmon resonance assays allows scientists to characterize binding kinetics and elucidate the molecular mechanisms underlying receptor activation or inhibition. These applications are critical for advancing knowledge of cellular communication and for supporting early-stage drug discovery efforts.
Peptide-protein interaction mapping: The unique sequence of PDC31 makes it a valuable probe for identifying and characterizing peptide-mediated interactions with target proteins. Through techniques such as pull-down assays, co-immunoprecipitation, or cross-linking mass spectrometry, researchers can map interaction interfaces and determine binding partners within complex proteomes. These insights facilitate the understanding of signaling networks, regulatory complexes, and dynamic protein assemblies, which are central to many areas of molecular and cellular biology.
Peptide synthesis optimization: As a model substrate or reference standard, PDC31 is frequently used in the development and validation of peptide synthesis protocols. Its well-defined sequence and physicochemical properties enable evaluation of coupling efficiencies, deprotection strategies, and purification techniques in solid-phase peptide synthesis workflows. Employing this compound in method optimization helps ensure consistency, yield, and purity in the production of both research-grade and custom peptides, supporting high standards in laboratory practice.
Analytical method development: The defined composition and stability of PDC31 make it a suitable candidate for calibrating and validating analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry. By serving as a reference or control, the peptide facilitates the assessment of instrument performance, detection sensitivity, and quantification accuracy. These applications are essential for ensuring reproducibility and reliability in peptide analysis, which underpins rigorous biochemical research and quality assurance processes.
1. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum
3. High fat diet and GLP-1 drugs induce pancreatic injury in mice
4. Myotropic activity of allatostatins in tenebrionid beetles
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