(Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human)

(Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human) is a modified N-terminal hexapeptide designed to probe protease-activated receptor initiation motifs. The substitutions shape side-chain orientation and influence binding to regulatory partners. Its short length allows precise dissection of activation sequences. Researchers employ it to examine signaling determinants and peptide-protein recognition.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
(Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human)(CAS 245329-02-6)

CAT No: P4301

CAS No:245329-02-6

Synonyms/Alias:245329-02-6;L-Phenylalanyl-L-seryl-L-leucyl-L-leucyl-L-arginyl-L-tyrosinamide;(Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human);FSLLRY-NH2 TFA;CHEMBL2431725;(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide;FSLLRY-amide;Phe-Ser-Leu-Leu-Arg-Tyr-NH2;C39H60N10O8;BDBM50440871;HB3309;AKOS024458326;FP109784;DB-230591;G13480;H-Phe-Ser-Leu-Leu-Arg-Tyr-NH2; H-FSLLRY-NH2;FSLLRY-NH2 (modifications: Tyr-6 = C-terminal amide);(Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human) trifluoroacetate salt;(S)-N-((S)-1-Amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-2-((S)-2-((S)-2-((S)-2-((S)-2-amino-3-phenylpropanamido)-3-hydroxypropanamido)-4-methylpentanamido)-4-methylpentanamido)-5-guanidinopentanamide;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C39H60N10O8
M.W/Mr.
797
Sequence
One Letter Code:FSLLRY
Three Letter Code:H-Phe-Ser-Leu-Leu-Arg-Tyr-NH2
Source#
Synthetic
InChI
InChI=1S/C39H60N10O8/c1-22(2)17-30(36(55)45-28(11-8-16-44-39(42)43)35(54)46-29(33(41)52)20-25-12-14-26(51)15-13-25)47-37(56)31(18-23(3)4)48-38(57)32(21-50)49-34(53)27(40)19-24-9-6-5-7-10-24/h5-7,9-10,12-15,22-23,27-32,50-51H,8,11,16-21,40H2,1-4H3,(H2,41,52)(H,45,55)(H,46,54)(H,47,56)(H,48,57)(H,49,53)(H4,42,43,44)/t27-,28-,29-,30-,31-,32-/m0/s1
InChI Key
KMSCNWHRNILNRJ-JNRWAQIZSA-N

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