Philanthotoxin 74 features a polyamine-amino acid framework frequently studied as a probe of ion-channel function. The cationic side chains enable strong electrostatic interactions with acidic residues in transmembrane domains. Structural flexibility permits evaluation of binding geometries and conductance modulation. Researchers employ it in neurochemical mechanism studies, ligand-design projects, and structure-activity investigations.
CAT No: R2358
CAS No:1227301-51-0
Synonyms/Alias:Philanthotoxin 74;1227301-51-0;401601-12-5;Philanthotoxin 74 dihydrochloride;PhTx-74 HCl;phtx-74 dihydrochloride;Benzenepropanamide, N-[7-[(4-aminobutyl)amino]heptyl]-4-hydroxy-alpha-[(1-oxobutyl)amino]-, hydrochloride (1:2), (alphaS)-;N-[(2S)-1-[7-(4-aminobutylamino)heptylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]butanamide;dihydrochloride;Philanthotoxin 74 (hydrochloride);(S)-N-(1-((7-((4-aminobutyl)amino)heptyl)amino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)butyramide dihydrochloride;(S)-N-[7-[(4-Aminobutyl)amino]heptyl]-4-hydroxy-alpha-[(1-oxobutyl)amino]benzenepropanamide dihydrochloride;Philanthotoxin-7,4;C24H42N4O3.2HCl;SCHEMBL2018664;DTXSID50673102;CHEBI:184087;GLXC-04185;HB0499;AKOS024457286;CS-7860;HY-104020A;AS-77383;Benzenepropanamide, N-[7-[(4-aminobutyl)amino]heptyl]-4-hydroxy-a-[(1-oxobutyl)amino]-, hydrochloride (1:2), (aS)-;DA-76820;G13687;N-{7-[(4-Aminobutyl)amino]heptyl}-Nalpha-butanoyl-L-tyrosinamide--hydrogen chloride (1/2);N-[(1S)-1-({7-[(4-AMINOBUTYL)AMINO]HEPTYL}CARBAMOYL)-2-(4-HYDROXYPHENYL)ETHYL]BUTANAMIDE DIHYDROCHLORIDE;
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